Publications by authors named "Hellinger A"

We present a 55-year-old woman with a palpable mass in the right upper abdomen. Contrast-enhanced computed tomography showed a highly vascularized and primary resectable tumor of the spleen. We performed an open splenectomy with locoregional lymphadenectomy.

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Patients with Fontan physiology are at heightened risk of thrombosis related to passive venous return leading to increased stasis, as well as acquired thrombophilia from congestive hepatopathy. Variability exists for post-Fontan thromboprophylaxis, with no consensus on best practices. Direct oral anticoagulants offer advantages over conventional anticoagulants including fewer drug-drug interactions, no dietary restrictions, and less frequent monitoring.

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Introduction: This study addresses the lack of methods to quantify driver familiarity with roadways, which poses a higher risk of crashes.

Method: We present a new approach to assessing driving route diversity and familiarity using data from the DrivingApp, a smartphone-based research tool that collects trip-level information, including driving exposure and global positioning system (GPS) data, from young novice drivers (15-19 years old) to older drivers (67-78 years old). Using these data, we developed a GPS data-based algorithm to analyze the uniqueness of driving routes.

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Article Synopsis
  • Verification of supervised driving hours for teenagers is difficult, and the study aims to explore the adoption of electronic logbooks as a solution through a survey of teenagers and their parents in the USA.
  • Most participants supported requirements for supervised driving and preferred electronic logbooks over traditional paper ones, with features like drive summaries and automatic trip detection considered most useful.
  • The findings highlight strong public support for electronic logbooks, suggesting that policymakers and driving educators could consider implementing this technology to enhance the tracking of practice driving hours.
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Introduction: Motor vehicle crashes (MVCs) are the leading cause of work-related deaths in the United States. The increasing popularity of the competitive rideshare market and the lack of oversight over workforce health and safety limits understanding of the current occupational hazards and associated risk factors faced by this precarious workforce. The objective of this analysis was to determine what the personal, social and occupational risk factors for work-related crashes in rideshare drivers are in the United States and suggest further research required to understand occupational health risks and opportunities for interventions.

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Background: Interprofessional training wards (ITW) are increasingly being integrated into teaching and training concepts in visceral surgery clinics.

Objective: How safe is patient care on an ITW in visceral surgery?

Material And Methods: Data collection took place from November 2021 to December 2022. In this nonrandomized prospective evaluation study the frequency and severity of adverse events (AE) in 3 groups of 100 patients each in a tertiary referral center hospital for visceral surgery were investigated.

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Background: The use of apixaban in the pediatric cardiac population is expanding. We describe our apixaban dosing and monitoring strategy in children and young adults awaiting heart transplantation, along with outcomes related to bleeding and thrombosis during wait-list and early post-transplant periods.

Methods: This study is a retrospective, single-center analysis of all patients receiving apixaban while awaiting cardiac transplantation.

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Introduction: Supervised practice during the learner stage of graduated driver licensing is required in all U.S. states and some international jurisdictions.

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Despite the great success of the concept of doping organic compounds with BN units to access new materials with tailored properties, its use in polymer chemistry has only been realized quite recently. Herein, we present a comprehensive study of oligo- and poly(arylene iminoborane)s comprising a backbone of phenylene or thiophene moieties, as well as combinations thereof, linked via B=N units. The novel polymers can be regarded as BN analogues of poly(p-phenylene vinylene) (PPV) or poly(thiophene vinylene) (PTV) or their copolymers.

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Introduction: With growing emphasis on surgical safety, it appears fundamental to assess the safety of colorectal resection involving primary stapled anastomosis. Surgical stapling devices can considerably foster patient safety in colorectal surgery, but their misuse or malfunction encompass a unique risk of postoperative complications. The Digital Device Briefing Tool (DDBT) is a digital cognitive aid developed to enhance safe use of the Ethicon circular stapling device during colorectal resection.

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Background: Direct oral anticoagulants use in pediatric cardiology is poorly defined.

Objective: We present the largest experience of apixaban use in children with heart disease, using weight- and level-based dosing.

Methods: Retrospective single-center analysis of cardiac patients ≤19 years treated with apixaban.

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This article reviews existing state laws related to autonomous vehicle (AV) safety, equity, and automobile insurance. Thirty states were identified with relevant legislation. Of these, most states had one or two relevant laws in place.

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Purpose: This study investigates the long-term effects of biliopancreatic diversion with duodenal switch (BPD-DS) on patients with advanced type 2 diabetes mellitus (T2DM) while paying special attention to preoperative diabetes severity.

Materials And Methods: A retrospective analysis was conducted using prospective and current data on patients who underwent an open BPD-DS 6-12 years ago. Patients were stratified according to preoperative diabetes severity into 4 groups (group 1: oral antidiabetic drugs only; group 2: insulin < 5 years; group 3: insulin 5-10 years; group 4: insulin > 10 years).

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Anticoagulation with Vitamin K antagonists (VKA) has always posed challenges in terms of monitoring requirements. These challenges were further exacerbated in the setting of the COVID-19 pandemic, with limited access to and/or avoidance of laboratory testing. The importance of utilizing point of care (POC) health technology for individualized patient management is salient.

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Objectives: To identify, describe and critique state and local policies related to child passenger safety in for-hire motor vehicles including ridesharing and taxis.

Methods: We used standard legal research methods to collect policies governing the use of child restraint systems (CRS) in rideshare and taxi vehicles for all 50 states and the 50 largest cities in the USA. We abstracted the collected policies to determine whether the policy applies to specific vehicles, requires specific safety restraints in those vehicles, lists specific requirements for use of those safety restraints, seeks to enhance compliance and punishes noncompliance.

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Gamma-aminobutyric acid (GABA) is a well-known inhibitory neurotransmitter implicated in numerous physiological and pathological behaviors including social interest. Dysregulation of the median raphe region (MRR), a main serotoninergic nucleus, is also characterized by increased social problems. As the majority of MRR cells are GABAergic, we aimed to reveal the social role of these cells.

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Despite their considerable prevalence, dynamics of hospital-associated COVID-19 are still not well understood. We assessed the nature and extent of air- and surface-borne SARS-CoV-2 contamination in hospitals to identify hazards of viral dispersal and enable more precise targeting of infection prevention and control. PubMed, ScienceDirect, Web of Science, Medrxiv, and Biorxiv were searched for relevant articles until June 1, 2021.

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Objective: To characterize viscoelastic testing profiles of children with multisystem inflammatory syndrome in children (MIS-C).

Methods: This single-center retrospective review included 30 patients diagnosed with MIS-C from March 1 to September 1, 2020. Thromboelastography (TEG) with platelet mapping was performed in 19 (63%) patients and compared to age- and sex-matched controls prior to cardiac surgery.

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Background: The learner stage of graduated driver licensing (GDL), when teenagers are supervised by an adult driver, represents an opportunity to develop skills that could confer a safety benefit during their years of independent driving. This paper describes the design of a teenage driving study, which aims to evaluate the impact of a smartphone application, the 'DrivingApp,' to increase the quantity and improve the quality of supervised practice driving.

Methods: This longitudinal intervention study of teenage drivers and a parent/guardian spans the final 6 months of the learner licence and the first year of independent driving.

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Apixaban is well studied in adults; paediatric data are extremely limited. We describe 3 children (age 2-6 years, weight 13-17 kg) with congenital heart disease who developed intracardiac thrombosis, and in whom typical treatments had failed (in 1) or were considered impractical (in 2). All were treated with apixaban 2.

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Background: Arterial ex situ back-table perfusion (BP reportedly reduces ischemic-type biliary lesion after liver transplantation. We aimed to verify these findings in a prospective investigation.

Methods: Our prospective, randomized, controlled, multicenter study involved livers retrieved from patients in 2 German regions, and compared the outcomes of standard aortic perfusion to those of aortic perfusion combined with arterial ex situ BP.

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Objective: To assess the role of registries in the postmarketing surveillance of surgical meshes.

Background: To date, surgical meshes are classified as group II medical devices. Class II devices do not require premarket clearance by clinical studies.

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Background: Incisional hernias are one of the most frequent complications in abdominal surgery. Laparoscopic repair has been widely used since its first description but has not been standardized. A panel of hernia experts with expertise on the subject "incisional hernia" was established to review existing literature and define a standard approach to laparoscopic IPOM-repair for incisional hernia.

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