Metalloproteinases in Restorative Dentistry: An In Silico Study toward an Ideal Animal Model.

In dentistry, various animal models are used to evaluate adhesive systems, dental caries and periodontal diseases. Metalloproteinases (MMPs) are enzymes that degrade collagen in the dentin matrix and are categorized in over 20 different classes. Collagenases and gelatinases are intrinsic constituents of the human dentin organic matrix fibrillar network and are the most abundant MMPs in this tissue.

Fabrication and characterization of low-shrinkage dental composites containing montmorillonite nanoclay.

Dental composites are aesthetic materials widely used in Dentistry for replacing hard dental tissues lost due to caries or traumas. The aim of this study was to fabricate low-shrinkage dental composite charged with nanoclay fillers (montmorillonite Cloisite®-MMT) and evaluate their cytotoxicity and physicomechanical properties. Four dental composites were produced from the same organic matrix: Bis-GMA/TEGDMA (30 wt.

Influence of activation mode, fatigue, and ceramic interposition on resin cements' diametral tensile strength.

This study evaluated the influence of activation modes, on Diametral Tensile Strength (DTS) of dual cured resin cements subjected to a Mechanical Fatigue test (MF). Four dual-cured resin cements (RelyX UNICEM [U], RelyX ARC [A], ENFORCE [E] and Nexus 2 [N]) were activated by three different curing modes as follows: Self-Curing (SC), Dual Cure activation with photoactivation executed directly (DC) and Dual Cure activation with Photoactivation Through Porcelain (DCTP). After 24 hours, half of the sample was subjected to 30.

Influence of stress corrosion on the mechanical properties of laser-welded titanium.

Statement Of Problem: Whether laser-welded (LW) titanium can resist the stress corrosion produced by the combination of fluoride ions and stress in the oral environment is unknown.

Purpose: The purpose of this in vitro study was to investigate the influence of stress corrosion on the mechanical properties of LW titanium.

Material And Methods: Twenty-seven titanium bars (25×2 mm) with a circular cross-section were cut in half and laser-welded, while another 27 nonwelded (NW) bars were used as the control.

Low-shrinkage composites: an in vitro evaluation of sealing ability after occlusal loading.

The objective of this in vitro study was to compare the microleakage of a flowable low-shrinkage-stress resin composite--in a Class II fatigue-loading design when used as a 4 mm dentin replacement--to a conventionally layered silorane-based resin composite. Eighty standardized 4 mm deep cavities, divided into 4 subgroups, were restored with the 2 tested materials. Half of the restorations were submitted to mechanical loading, and all of the restorations were prepared for microleakage evaluation.

Flexural bond strength of repaired composite resin restorations: influence of surface treatments and aging.

The objective of this study was to evaluate the effect of storage in deionized water at room temperature, for seven days and six months, on the flexural strength of a repaired photocured microhybrid composite resin, using different surface treatments. After each surface treatment, the adhesive interface was analyzed with a surface roughness tester. The flexural strength of samples from each group was determined by three-point bending in a testing machine at a crosshead speed of 0.

Photodynamic therapy with two different photosensitizers as a supplement to instrumentation/irrigation procedures in promoting intracanal reduction of Enterococcus faecalis.

Introduction: This in vitro study aimed to investigate the antibacterial effects of photodynamic therapy (PDT) with methylene blue (MB) or toluidine blue (TB) (both at 15 microg/mL) as a supplement to instrumentation/irrigation of root canals experimentally contaminated with Enterococcus faecalis.

Methods: Seventy extracted teeth had their root canals contaminated with an endodontic strain of E. faecalis for 7 days, instrumented with nickel-titanium instruments and irrigated either with 2.

Evaluation of the cervical integrity during occlusal loading of Class II restorations.

There are many concerns regarding the clinical behavior of packable composite restorations in Class II cavities, particularly when those restorations are subjected to axial mechanical loads. This study evaluated microleakage in vitro in proximal vertical "slot"-type cavities with walls located in enamel and dentin, filled with packable composite, associated or not associated with a flowable composite, a reinforced light-curing glass-ionomer or a compomer, after being submitted to occlusal load cycling. These preparations were subjected to either occlusal load cycling or no occlusal load cycling.

Occlusal loading evaluation in the cervical integrity of Class II cavities filled with composite.

There are many doubts about the clinical behavior of condensable composite restorations in Class II cavities, particularly when they are submitted to axial mechanical loads. This study evaluated cervical microleakage in Class II direct fillings in composite, whether or not they were submitted to an occlusal load cycling. Twenty-three human molars with standardized cavities (proximal vertical "slot") were treated with enamel and cement endings.

Hybrid layer thickness and morphology: the influence of cavity preparation with Er:YAG laser.

Dentinal surfaces prepared with Er:YAG laser have significantly different characteristics from those prepared with conventional instruments. Different hybrid layer morphologies and thicknesses occur, which may result in differences in the quality of restorations placed on dentinal surfaces prepared with a diamond bur when compared with using an Er:YAG Laser. This study compared the hybrid layer thickness and morphology formed utilizing Scotchbond Multipurpose Plus (SBMP) on dentin prepared with a diamond bur in a high speed handpiece and dentin prepared with an Er:YAG laser.