A longitudinal study of dietary inflammatory index and quality of life in people with osteoarthritis: data from the Osteoarthritis Initiative database.

Dietary inflammatory index (DII) was demonstrated to be correlated to quality of life (QoL) in people with osteoarthritis (OA), but there is lack of an exploration of the relationship between the longitudinal trajectories of QoL and DII in OA people. This study aims to investigate the relationship between DII and longitudinal trajectories of QoL, and the moderating effect of physical activity on this relationship in OA people. Data from the Osteoarthritis Initiative database includes baseline measurements and follow-up data at 1, 2, 3, 4, 5, 6, and 8-year intervals for the 12-item Short-Form Health Outcome Survey questionnaire (physical and mental dimensions) and baseline sociodemographic characteristics utilized in this study.

Evaluation of urban ecological livability and obstacle factor diagnosis from a synergistic perspective: A case study of Zhangjiajie City, China.

The construction of ecological livability plays a crucial role in achieving ecological civilization. During economic development, conflicts between urban populations, resources, and the environment have become increasingly prominent. Although China's efforts in building ecological livability have made certain achievements, they are still in the early stages, making research in this area very necessary.

Tree-ring maximum latewood density reveals unprecedented warming and long-term summer temperature in the upper Indus Basin, northern Pakistan.

Understanding long-term temperature variability in the Upper Indus Basin (UIB), northern Pakistan, and its driving mechanisms is challenging due to the scarcity of long observational records and available literature. In this study, we reconstructed a 651-year (1370-2020 CE) warm-season (March-September) temperature record using the tree-ring maximum latewood density (MXD) of blue pine (Pinus wallichiana). The reconstruction explains 57 % of the variance in actual temperature during the common calibration period (1972-2020 CE).

Greater moisture impacts on radial growth of Larix sibirica in the eastern Altay Mountains since the 1990s.

Against the background of climate warming and humidification, the so-called 'divergence problem' reduces the stability of tree rings in response to climate, and affects the reliability of tree-ring reconstruction. Investigation of the divergence problem is crucial to improve our understanding of the response patterns of trees to climate warming, and provide a scientific basis for accurate climate reconstruction. Based on tree-ring width data for Siberian larch (Larix sibirica Ledeb.

Dermal Papilla Cells: From Basic Research to Translational Applications.

As an appendage of the skin, hair protects against ultraviolet radiation and mechanical damage and regulates body temperature. It also reflects an individual's health status and serves as an important method of expressing personality. Hair loss and graying are significant psychosocial burdens for many people.

Dietary sodium intake restriction in patients with heart failure: an overview of systematic reviews.

This study aimed to identify, assess, and summarize systematic reviews on dietary sodium intake restrictions for patients with heart failure. Literature searches were conducted on Pubmed, CINAHL, ScienceDirect, Cochrane Library, China National Knowledge Infrastructure, and the Wanfang Database up to January 2024. The methodological quality of the included reviews was assessed using the quality assessment tool from the Australian JBI Center for Evidence-Based Healthcare (2016).

Development of a prediction model for predicting the prevalence of nonalcoholic fatty liver disease in Chinese nurses: the first-year follow data of a web-based ambispective cohort study.

Background: Nonalcoholic fatty liver disease (NAFLD) is gradually becoming a huge threat to public health. With complex working characteristics, female nurses had been found with high risk of NAFLD. To develop and validate a prediction model to predict the prevalence of NAFLD based on demographic characteristics, work situation, daily lifestyle and laboratory tests in female nurses.

Relationship between night shift and sleep problems, risk of metabolic abnormalities of nurses: a 2 years follow-up retrospective analysis in the National Nurse Health Study (NNHS).

Background And Purpose: Efforts to improve nurses' physical and mental health are critical to ensuring the safety and quality of the healthcare system. Long-term studies targeting the relevancy of nurses' occupation characteristics with health conditions remain insufficient. This study aimed to examine the relationship between nurses' night shift and sleep problems and metabolic abnormalities risk.

Sensitive Quantitative In Vivo Assay for Evaluating the Effects of Biomolecules on Hair Growth and Coloring Using Direct Microinjections into Mouse Whisker Follicles.

Many people suffer from hair loss and abnormal skin pigmentation, highlighting the need for simple assays to support drug discovery research. Current assays have various limitations, such as being in vitro only, not sensitive enough, or unquantifiable. We took advantage of the bilateral symmetry and large size of mouse whisker follicles to develop a novel in vivo assay called "whisker follicle microinjection assay".

Metabolic Disease and Risk of Thyroid Disease: Evidence from the National Nurse Health Cohort in China.

Background: Previous studies have shown that metabolic diseases are risk factors for thyroid disease; most studies are cross-sectional design. We aimed to evaluate the causal relationship between thyroid and metabolic diseases in a cohort of Chinese nurses.

Methods: We conducted an ambispective cohort study of the National Nurses' Health Study.

What Frequency of Ankle Pump Exercise is Optimal to Improve Lower Limb Hemodynamics? A Systematic Review and Network Meta-analysis.

Purpose: Ankle pump exercises (APE) have been widely used in clinical practice. However, best practices for APE have not been established. Recognize the most effective frequency of APE for improving lower extremity hemodynamics and establish recommendations in clinical practice.

A Cre knockin mouse reveals specific expression of Agouti gene in mesenchymal lineage cells in multiple organs and provides a unique tool for conditional gene targeting.

The mouse Agouti gene encodes a paracrine signaling factor which promotes melanocytes to produce yellow instead of black pigment. It has been reported that Agouti mRNA is confined to the dermal papilla after birth in various mammalian species. In this study, we created and characterized a knockin mouse strain in which Cre recombinase was expressed in-frame with endogenous Agouti coding sequence.

The Immunomodulatory Effects of Phellodendri Cortex Polysaccharides on Cyclophosphamide-Induced Immunosuppression in Mice.

Cyclophosphamide is a commonly used anticancer drug, and immunosuppression is one of the most common side effects. How to recover the immunological function is important for cyclophosphamide-treated patients. In the present study, Phellodendri Cortex polysaccharides (CPP) could enhance the proliferation of mouse spleen lymphocytes in vitro.

[May-July NDVI variation for the middle Qinling Mountains over the past 194 years indicated by tree rings of ].

Due to the short-term observation record of the normalized difference vegetation index (NDVI), the research on long-term NDVI changes is scarce, which limits our understanding of the impacts of NDVI changes in the context of global warming. In this study, a regional tree-ring chronology was developed based on the tree-ring samples of in the middle Qinling Mountains. The results showed that tree-ring width of was significantly positively correlated with May-July NDVI (=0.

[Responses of radial growth of to climatic and hydrological factors at different altitudes in Western Yunnan, China].

A tree-ring width chronology (STD) was established using tree-ring cores of from two sites with different altitudes in Western Yunnan, to study the responses of radial growth to climatic and hydrological factors. The results showed that the radial growth of in Western Yunnan was mainly affected by precipitation, temperature and runoff. The radial growth of at high altitude (2413.

Protocol for the National Nurse Health Study (NNHS): a web-based ambispective cohort study.

Introduction: The physical and mental health of nurses may significantly impact the entire medical care group and directly affect the quality of medical services. Due to the intense emotional involvement and often problematic working conditions that characterise their profession, nurses appear to be especially susceptible to a complex set of stressors with repercussions to their health. Several landmark studies of nurses have provided an abundance of evidence on risk factors that influence the health status of nurses.

FN1 promotes chondrocyte differentiation and collagen production via TGF-β/PI3K/Akt pathway in mice with femoral fracture.

Fibronectin (FN) functions as a potent stimulator of osteogenic differentiation, and bone fracture healing. In FN family, FN1 acts as an interactive protein gene product to mediate chondrocyte adhesion. However, its effect on fracture healing remains elusive.

SDF-1 mediates mesenchymal stem cell recruitment and migration via the SDF-1/CXCR4 axis in bone defect.

Introduction: Recent studies have indicated the potential of stem cell therapy in combination with cytokines to restore the bone repair via migration and homing of stem cells to the defected area. The present study aimed to investigate the mobilization and recruitment of mesenchymal stem cells (MSCs) in response to SDF-1.

Materials And Methods: Herein, the knockout rat model of the bone defect (BD) was treated with the induced membrane technique.

Validation and Evaluation of the Core Nursing Outcomes Evaluation System for Inpatients with Stroke.

Objective: To evaluate the reliability, validity, responsiveness, importance, and application level of the Core Nursing Outcomes Evaluation System for inpatients with stroke.

Methods: The reliability, validity, responsiveness, importance, and application level were evaluated by expert scoring, clinical measurement, and questionnaire survey.

Results: The scale-level content validity index (S-CVI) and item-level content validity index (I-CVI) were >0.

Quality of life after I-125 seed implantation using computed tomography and three-dimensional-printed template guidance in patients with advanced malignant tumor.

Background: I-125 seed implantation has been widely applied in the local treatment of advanced malignant tumor. It has the advantages of providing a high dose of treatment to the target sites and low dose to normal tissues. It has been mostly applied as palliative treatment for recurrences in advanced malignant tumor (except for prostate cancer), suppressing tumor development and improving the quality of life of patients.

Augmented Rac1 Expression and Activity are Associated with Oxidative Stress and Decline of β Cell Function in Obesity.

Background: The aim of this study was to clarify the relationship among Rac1 expression and activation, oxidative stress and β cell dysfunction in obesity.

Methods: In vivo, serum levels of glucose, insulin, oxidative stress markers and Rac1 expression were compared between ob/ob mice and C57BL/6J controls. Then, these variables were rechecked after the administration of the specific Rac1 inhibitor-NSC23766 in ob/ob mice.

Dissipation of diethyl aminoethyl hexanoate (DA-6) residues in pakchoi, cotton crops and soil.

QuEChERS procedure and acetonitrile extraction, oscillation and ultrasonic procedure followed by GC-MS and LC-MS/MS (QqQ) detections were established for determination of diethyl aminoethyl hexanoate (DA-6) residues in pakchoi, cotton leaf, cotton seed and soil. At concentration levels of 0.005-1 mg kg(-1), recoveries were in the range of 80.