Immediate Irradiation Induced Cerebral Water and Hemodynamic Response in Whole Brain Radiotherapy.

Purpose: Effects of clinical radiotherapy are often studied between or after irradiations. The current study's aim was to monitor an immediate irradiation response in cerebral water and hemodynamics in patients treated with whole brain radiotherapy (WBRT) and to assess the response's individuality.

Methods: We used functional near-infrared spectroscopy (fNIRS) to monitor changes in cerebral water, oxyhemoglobin (HbO), and deoxyhemoglobin (HbR) during the irradiation of 31 patients (age 69.