Publications by authors named "Helgi Nikoli"
Functional Motif Discovery in FOXO1 Through CRISPR/Cas9 Exon Tiling Scan.
Methods Mol Biol
November 2024
Article Synopsis
- FOXO1 is an important transcription factor involved in key cellular processes like cell differentiation, apoptosis, and metabolism, making it a focus for research.
- The chapter discusses using CRISPR exon scanning as a novel method to explore functional domains of FOXO1, aiming to clarify its regulatory roles.
- This method helps identify crucial areas of the FOXO1 gene and provides insights into how different regions impact its functions in various biological scenarios.