Growth hormone deficiency and replacement in hypopituitary patients previously treated for acromegaly or Cushing's disease.

Objective: To compare baseline characteristics in adult patients with growth hormone (GH) deficiency (GHD) who had previously been treated for Cushing's disease or acromegaly with data from patients with GHD of other aetiologies. To study the effects of GH therapy in those patients who had completed at least 6 months of GH replacement.

Design: Data from a large outcomes research database (KIMS (Pharmacia International Metabolic Database)).