Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors.

Objective: The aim of this study was to investigate the presence of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors.

Methods: Twenty-seven minor salivary gland tumors were investigated using immunohistochemistry for CD1a and E-cadherin.

Results: A significant difference regarding the mean density of CD1a-positive Langerhans cells was observed between pleomorphic adenomas and malignant tumors studied (P = 0.

Aortocutaneous fistula complicating a pseudoaneurysm of the thoracic aorta--a necropsy report.

This article presents the necropsy report on a 60-year-old male patient with a large thoracoabdominal aortic aneurysm complicated by a protruding dorsal mass (pseudoaneurysm) and aortocutaneous fistula. This is the first reported case of a spontaneous aortocutaneous fistula complicating the natural course of a thoracic aortic aneurysm.

TP53 mutations in primary breast carcinomas from white and African-Brazilian patients.

We have attempted to determine the incidence, nature and clinical significance of TP53 mutation in a group of white (242 cases) and African-Brazilian (52 cases) patients with breast cancer. The interethnic admixture as estimated by STR markers showed that white subjects displayed 67.9+/-0.