Publications by authors named "Helene Moniz-Koum"
Article Synopsis
- A new device was assessed for its ability to analyze breast masses using label-free fluorescence spectral analysis on freshly removed surgical samples.
- The study involved 64 breast masses, where results showed that maximum fluorescence intensity effectively distinguished between benign and malignant tumors with a significant p-value, and optimal data collection suggested taking five random measurements for best accuracy.
- The device achieved high sensitivity (98.8%) and strong negative predictive values (97.2%), indicating it can accurately differentiate breast mass types and is suitable for further clinical development.
Article Synopsis
- This study investigates the use of an embedded device that measures endogenous fluorescence to differentiate between malignant lung lesions and healthy lung tissue in patients suspected of having non-small cell lung cancer (NSCLC).
- The study involved 96 patients and found that the fluorescence intensity was significantly higher in NSCLC lesions compared to surrounding healthy tissue and non-tumoral lesions.
- The findings suggest that the embedded device could help improve diagnostic accuracy for lung cancer, as it identified specific fluorescence characteristics (like photobleaching) that were more pronounced in malignant lesions.
