The reliable characterization of particle size distribution and nicotine delivery emitted by electronic cigarettes (ECs) is a critical issue in their design. Indeed, a better understanding of how nicotine is delivered as an aerosol with an appropriate aerodynamic size is a necessary step toward obtaining a well-designed nicotine transfer from the respiratory tract to the bloodstream to better satisfy craving and improve smoking cessation rates. To study these two factors, recent models of EC devices and a dedicated vaping machine were used to generate aerosols under various experimental conditions, including varying the EC power level using two different types of atomizers.
View Article and Find Full Text PDFInt J Environ Res Public Health
June 2019
This work focuses on an experimental study of the influence of e-liquid composition on the mass of vaporized e-liquid after standardized emission generation using a U-SAV (Universal System for Analysis of Vaping) vaping machine. All the experiments were based on the use of a Cubis 1Ω clearomiser and on the standard protocol for electronic cigarettes emission generation. Currently, there is no standardized method available to calibrate the emission generations of electronic cigarettes.
View Article and Find Full Text PDFInt J Environ Res Public Health
October 2017
The accurate study of aerosol composition and nicotine release by electronic cigarettes is a major issue. In order to fully and correctly characterize aerosol, emission generation has to be completely mastered. This study describes an original vaping machine named Universal System for Analysis of Vaping (U-SAV), dedicated to vaping product study, enabling the control and real-time monitoring of applied flow rate and power.
View Article and Find Full Text PDFThe elaboration of an original composite bimetallic macroporous electrode containing a site-selective sol-gel deposit is reported. Regular colloidal crystals, obtained by a modified Langmuir-Blodgett approach, are used as templates for the electrogeneration of the desired metals in the form of a well-defined layered bimetallic porous electrode. This porous matrix shows a spatially modulated electroactivity which is subsequently used as a strategy for targeted electrogeneration of a sol-gel deposit, exclusively in one predefined part of the porous electrode.
View Article and Find Full Text PDFWe use soft lithography to pattern molecularly imprinted polymers (MIPs) at the nanoscale. Patterning occurs via a micro transfer molding process associated with an edge effect. We show using fluorescence microscopy that the nanopatterned synthetic receptors specifically recognize and bind a model target, dansyl-l-phenylalanine.
View Article and Find Full Text PDFIt is well established that polydimethylsiloxane (PDMS) stamps submitted to an adequate plasma treatment spontaneously develop an ordered surface roughness. In this work, we show that thin layers made of polyamidoamine (PAMAM) dendrimers can be patterned at the nanoscale using these buckled PDMS stamps. The structures accurately reproduce the self-assembled waves observed on the stamp surface after plasma treatment.
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