A low-dose ipsilateral lung restriction improves 3-d conformal planning for partial breast radiation therapy.

In trials of 3D conformal external beam partial breast radiotherapy (PBRT), the dosimetrist must balance the priorities of achieving high conformity to the target versus minimizing low-dose exposure to the normal structures. This study highlights the caveat that in the absence of a low-dose lung restriction, the use of relatively en-face fields may meet trial-defined requirements but expose the ipsilateral lung to unnecessary low-dose radiation. Adding a low-dose restriction that ≤ 20% of the ipsilateral lung should receive 10% of the prescribed dose resulted in successful plans in 88% of cases.

Does a three-field electron/minitangent photon technique offer dosimetric advantages to a multifield, photon-only technique for accelerated partial breast irradiation?

Purpose: To determine whether 3-field electron/minitangent photons (mixed-modality) technique improved dosimetry compared with a multifield, photon-only technique for accelerated partial breast irradiation (APBI).

Materials And Methods: Subjects were 20 breast cancer patients previously treated with photon-only APBI as part of a clinical trial to a dose of 38.5Gy/10 fractions in 5 days.