Publications by authors named "Helene Francisque"

Article Synopsis
  • - Psychosis, marked by delusions and hallucinations, is common in Alzheimer's and other neurodegenerative dementias, leading to challenges in diagnosis and treatment.
  • - A systematic review of 98 studies reveals high prevalence rates of psychotic symptoms across different dementias, with notable patterns such as misidentification delusions in dementia with Lewy bodies and paranoid ideas in Alzheimer's.
  • - The findings highlight significant variations in psychotic symptoms among different neurodegenerative diseases, emphasizing the need for more research on early-stage psychosis to improve diagnosis and management.
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Friedreich ataxia, an autosomal recessive mitochondrial disease, is the most frequent inherited ataxia. Many studies have attempted to identify cognitive and affective changes associated with the disease, but conflicting results have been obtained, depending on the tests used and because many of the samples studied were very small. We investigated personality and neuropsychological characteristics in a cohort of 47 patients with genetically confirmed disease.

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Deep brain stimulation (DBS) of the internal globus pallidus (GPi) could treat chorea in Huntington's disease patients. The objectives of this study were to evaluate the efficacy of GPi-DBS to reduce abnormal movements of three patients with Huntington's disease and assess tolerability. Three non-demented patients with severe pharmacoresistant chorea underwent bilateral GPi-DBS and were followed for 30, 24, and 12 months, respectively.

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