Publications by authors named "Helene Duault"
Article Synopsis
- Understanding the contributions of different host species in the transmission of Mycobacterium bovis is essential for effective control measures in multi-host systems.
- The study evaluates the effectiveness of three outbreak reconstruction methods (seqTrack, outbreaker2, and TransPhylo) using simulated data from 30 bovine tuberculosis outbreaks involving cattle and wildlife, while considering sampling biases.
- Results indicated that while seqTrack performed better in identifying specific host contributions, all three methods struggled with accuracy, primarily due to M. bovis's low mutation rate and the complexities of multi-host systems.
In two "départements" in the South-West of France, bovine tuberculosis (bTB) outbreaks due to Mycobacterium bovis spoligotype SB0821 have been identified in cattle since 2002 and in wildlife since 2013. Using whole genome sequencing, the aim of our study was to clarify badger contribution to bTB transmission in this area. We used a Bayesian evolutionary model, to infer phylogenetic trees and migration rates between two pathogen populations defined by their host-species.
View Article and Find Full Text PDFIn order to better understand transmission dynamics and appropriately target control and preventive measures, studies have aimed to identify who-infected-whom in actual outbreaks. Numerous reconstruction methods exist, each with their own assumptions, types of data, and inference strategy. Thus, selecting a method can be difficult.
View Article and Find Full Text PDF