Publications by authors named "Helena Mellander"

Objective: To systematically evaluate the ability of the CINA® LVO software to detect large vessel occlusions eligible for mechanical thrombectomy on CTA using conventional neuroradiological assessment as gold standard.

Methods: Retrospectively, two hundred consecutive patients referred for a brain CTA and two hundred patients that had been subject for endovascular thrombectomy, with an accessible preceding CTA, were assessed for large vessel occlusions (LVO) using the CINA® LVO software. The patients were sub-grouped by occlusion site.

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Purpose: Reduction in iodinated contrast medium (CM) dose is highly motivated. Our aim was to evaluate if a 50% reduction of CM, while preserving image quality, is possible in brain CT angiography (CTA) using virtual monoenergetic images (VMI) on spectral CT. As a secondary aim, we evaluated if VMI can salvage examinations with suboptimal CM timing.

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Purpose: Conventional computed tomography (CT) images are severely affected by metal artifacts in patients with intracranial coils. Monoenergetic images have been suggested to reduce metal artifacts.The aim of this study was to assess metal artifacts in virtual monoenergetic images (VMIs) reconstructed from spectral brain CT.

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Background: Acute ischemic lesions are challenging to detect by conventional computed tomography (CT). Virtual monoenergetic images may improve detection rates by increased tissue contrast.

Purpose: To compare the ability to detect ischemic lesions of virtual monoenergetic with conventional images in patients with acute stroke.

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Objective: The purpose of this study was to explore a novel method for brain tissue differentiation using quantitative analysis of multiphase computed tomography (CT) angiography (MP-CTA) on spectral CT, to assess whether it can distinguish underperfused from normal tissue, using CT perfusion (CTP) as reference.

Methods: Noncontrast CT and MP-CTA images from 10 patients were analyzed in vascular regions through measurements of Hounsfield unit (HU) at 120 kV, HU at 40 keV, and iodine density. Regions were categorized as normal or ischemic according to CTP.

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Purpose: Onyx® embolization causes severe artifacts on subsequent CT-examinations, thereby seriously limiting the diagnostic quality.The purpose of this work was to compare the diagnostic quality of the tailored metal artifact reducing algorithms iMAR to standard reconstructions of CTA in patients treated with Onyx® embolization.

Method: Twelve consecutive patients examined with Dual Energy CTA after Onyx® embolization were included.

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