Serum Levels of Selected Cytokines and Chemokines and IgG4 in Children With Recurrent Respiratory Tract Infections.

Respiratory tract infections are a common health problem. Cytokines/chemokines play a critical role in the regulation of the immune system. Their defective production may predispose to recurrent respiratory tract infections (RRIs), and an excessive immune response may lead to chronic inflammation and cause damage to the respiratory tract.

SARS-CoV-2 Infection as a Possible Trigger for IgA-Associated Vasculitis: A Case Report.

Background: IgA-associated vasculitis (IgAV), formerly known as Henoch-Schönlein purpura (HSP) disease, is the most common type of systemic vasculitis observed during developmental age. Available published studies associate the outbreak of the disease with streptococci, adenovirus, parvovirus, mycoplasma, respiratory syncytial virus (RSV), and influenza infection in approximately 50% of patients with HSP, while some emerging reports have described a few cases of COVID-19 infection being associated with HSP in both adults and children.

Case Presentation: a 7-year-old girl was diagnosed with HSP, fulfilling the four required clinical criteria (palpable purpura and abdominal pain, arthralgia and edema, and periodic renal involvement).

Pulmonary Function in Paediatric Patients with Inflammatory Bowel Disease.

Background: Among the extraintestinal manifestations of inflammatory bowel disease (IBD), those involving the lungs are relatively rare and often overlooked. There are only scarce data on the prevalence of IBD-associated lung involvement in children.

Objectives: The aim of our study was to assess pulmonary function in IBD children by different methods and to evaluate the influence of immunosuppressive therapy on disease severity.

Diagnostic difficulties in the diagnosis of high acute-phase proteins levels in a teenage drug addicted female patient.

Background: Youth drug addiction is a significant social and health problem. Symptoms of the disease include a number of neurological, gastrointestinal and cardiovascular disorders. Possible hormonal disorders and dysregulation of the immune system could also occur.

[Assessment of the natural history and clinical presentation of acetonemic vomiting].

Introduction: Ketosis in children may result from physiological adaptation to situations like fasting, fat-rich diet, straining physical activity, as well as from serious endocrine or metabolic disorders. The most frequently diagnosed cause of ketoacidosis are states of acetonemia and acetonuria with vomiting, during airways infections.

Goal: Assessment of the natural history and clinical presentation of acetonemic vomiting in children.

[Etiology and clinical course of urticaria in hospitalized children].

Introduction: Data concerning the epidemiology, etiology and clinical course of childhood urticaria are still under discussion.

Aim: To investigate the clinical presentation of urticaria in hospitalized children and to define its possible etiologies.

Material And Methods: Ninety eight children (male/female 42/57) aged 0.

Serum apelin-12 level is elevated in schoolchildren with atopic asthma.

Background: There are limited data on the role of adipokines in atopic asthma.

Aim: To determine serum level of apelin-12 (APE-12) in asthmatic children in relation to BMI and gender.

Methods: Serum APE-12 levels were measured using ELISA in 89 asthmatic children (61 boys and 28 girls, aged 7.

[RSV infection course in infants and young children during hospitalization].

Respiratory syncytial virus (RSV) infection is a widespread among the youngest group of pediatric patients, especially in the young infant, when the immune system is just being formed. A lot of children up to 5 year-old suffer infection many times, not only because of easy pathogen transfer, but also primary incidence of disease doesn't give permanent immunity. This study retrospectively analyses a group of children with confirmed during epidemic period RSV infection.