Aggregation of autoimmunity in extended families of people with autoimmune Addison disease.

Background: Autoimmunity accounts for 90% of cases of primary adrenal insufficiency (Addison disease (AD)). Affected people present a significant co-occurrence of autoimmune conditions; hence, clustering of autoimmunity is also predicted among their relatives.

Aims: To evaluate the burden of autoimmunity in families of people with AD.