Publications by authors named "Helen Wolfson"

Purpose: Skin oxygen level is of significance for the diagnosis and treatment of many clinical problems, such as chronic wounds and diabetic foot ulcers. Furthermore, skin oxygen levels can be correlated to arterial oxygen partial pressure, thereby revealing potentially dangerous conditions such as hyperoxia (too much oxygen), which may occur in ventilated neonates. Traditionally, skin oxygen levels are measured using electrochemical methods and, more recently, also by fluorescence lifetime techniques.

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Electron spin resonance (ESR) is a powerful analytical technique used for the detection, quantification, and characterization of paramagnetic species ranging from stable organic free radicals and defects in crystals to gaseous oxygen. Traditionally, ESR requires the use of complex instrumentation, including a large magnet and a microwave resonator in which the sample is placed. Here, we present an alternative to the existing approach by inverting the typical measurement topology, namely placing the ESR magnet and resonator inside the sample rather than the other way around.

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Objectives: Mitral annuloplasty involves sewing a prosthetic ring to the mitral annulus. This involves a risk of damaging the surrounding structures in the left atrioventricular (AV) groove, particularly the left circumflex artery, which may be inadvertently sutured, causing an arterial occlusion. We have used cardiac computed tomography (CT) scans to study the three-dimensional relationship between the mitral valvar annulus and the neighbouring coronary arteries in the AV groove, and to map the distance between the arteries and the annulus.

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