Publications by authors named "Helen V Shingles"
Impact of donor age ≥65 years on graft survival in large lung transplant cohorts.
J Heart Lung Transplant
November 2024
Background: Although the demand for allografts continuously surpasses the supply, the majority of lungs offered for transplant are declined based on various factors, including donor age. This in turn sustains the wait-list mortality of patients with end-stage pulmonary disease.
Methods: In this single-center, observational cohort study, we investigated the impact of donor age on graft survival.
Article Synopsis
- COVID-19 has significantly affected lung transplant recipients (LTR), who were previously at high risk for severe outcomes, but recent data shows improved results thanks to vaccinations and new treatments.
- A study of 279 LTR at Alfred Health revealed that only a small percentage experienced severe disease or mortality, with effective antiviral treatments and vaccinations providing considerable protection.
- Post-infection lung function also showed minimal decline, with only 17% of patients experiencing a significant drop, suggesting that prior rejection issues were the main factor influencing lung function post-COVID.