Publications by authors named "Helen Tryphonas"
This is the report of a workshop organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAM's main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods that are of importance to the biosciences and which replace, reduce or refine the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures that would enable it to become well informed about the state-of-the-art of non-animal test development and validation, and the potential for the possible incorporation of alternative tests into regulatory procedures.
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- Respiratory and food allergies are significant health concerns, with food allergies on the rise globally, affecting about 5% of young children and 1-2% of adults.
- Despite various tests for diagnosing allergies, there is a lack of validated animal models, making it difficult for regulatory agencies to assess food allergenicity effectively.
- The emergence of biotechnologically created foods has led health officials to pursue new methods to evaluate the potential allergenicity of these novel proteins.