Quality Characteristics and Essential Oil Properties of , , and Dried under Different Conditions.

The drying of medicinal and aromatic plants (MAPs) is one of the main preservation methods for these products that can prolong their shelf life, if performed properly. The current study aimed to examine the effects of different drying conditions (sun, shade, and oven drying at 42 °C) on the quality characteristics of , , and ; their essential oil (EO) yield; and their biological properties (antioxidant and antibacterial activities). According to the results of the current study, oven drying resulted in faster moisture loss for all investigated species and slightly darker products.

Environmentally Friendly Microemulsions of Essential Oils of and to Protect Crops against .

Essential oils (EOs) are reported to be natural pesticides, but their use to protect crops is very limited due to EOs' high instability and great volatility. Nanovectors represent a very smart alternative, and in this study, EOs from (AEO) and (SEO) were formulated into microemulsions and tested against . The EOs were extracted by steam distillation and analyzed by GC-MS.

Phytochemical Study of Stachys iva Griseb. and In Vitro Evaluation of AhR Transcriptional Activity.

Genus Stachys L. consists of approximately 365 species, distributed mainly in temperate regions. Several members of this genus are widely used in the traditional medicine of different countries worldwide.

NMR-guided isolation of undescribed triterpenoid saponins from Lysimachia atropurpurea L.

Phytochemical investigation on aerial parts of Lysimachia atropurpurea L. (Myrsinaceae), guided by NMR methods, resulted in the isolation and characterization of three previously undescribed triterpenoid saponins named stralysaponins A-C along with five known compounds. Their structures were elucidated by 1D and 2D NMR spectroscopy and HR-ESI-MS.

Chemometric Analysis Evidencing the Variability in the Composition of Essential Oils in 10 Species from Different Taxonomic Sections or Phylogenetic Clades.

Essential oil (EO) of spp. has been widely used for culinary purposes and in perfumery and cosmetics, as well as having beneficial effects on human health. The present study aimed to investigate the quantitative and qualitative variations in EOs in wild-growing and cultivated pairs of samples from members in four sections or three clades, namely L.

Comparative phytochemical analysis of cultivated and wild Boiss. & Heldr. subsp. infusions.

The present study focuses on the chemical composition of the infusions of subsp. from cultivated and wild populations using NMR, LC-DAD, LC-HRESIMS, and GC-MS techniques, to reveal possible differences. Mainly carbohydrates, flavonoids, and phenylethanoid glycosides were detected in the H-NMR spectra of both infusions.

Phytochemical Profiles and Biological Activities of Plant Extracts from Aromatic Plants Cultivated in Cyprus.

Medicinal and aromatic plants' properties, still an interesting research area, are attributed to the presence of various specialized products that possess important pharmacological activities. In the present study, six medicinal/aromatic plants (, , , , , and ) were evaluated for their phytochemical and nutritive composition, as well as their biological activities, including antioxidant, antimicrobial, and cytotoxic properties. The results obtained indicate that was rich in proteins and minerals such as N and Mg, while accumulated more K, Na, P, and Ca.

Recent Advances in Nanoformulations for Quercetin Delivery.

Quercetin (QUE) is a flavonol that has recently received great attention from the research community due to its important pharmacological properties. However, QUE's low solubility and extended first-pass metabolism limit its oral administration. This review aims to present the potential of various nanoformulations in the development of QUE dosage forms for bioavailability enhancement.

Study on the metabolism of natural sesquiterpene lactones in human liver microsomes using LC-Q-TOF-MS/MS.

Sesquiterpene lactones are naturally occurring, highly active -specialised metabolites, which are biosynthesized by important medicinal plants, fulfilling many functions. The metabolism of parthenolide (), grosheimin (), carbetolide C (), 8-O-(3,4-dihydroxy--methylenebutanoyloxy)-dehydromelitensin () and arteludovicinolide A () was examined using human liver microsomes. Phase , phase (glucuronidation), as well as combined phase + metabolism were studied.

Antiviral Activity of Beebread, Bee-Collected Pollen and Artificially Fermented Follen against Influenza A Virus.

Bee-collected pollen (BCP) and the naturally fermented BCP product known as bee bread (BB) are functional foods renowned for their nutritious, antioxidant, antibacterial and other therapeutic properties. This is the first study employed to assess the antiviral activity of BCP and BB against influenza A virus (IAV) H1N1 along with their proteinaceous, aqueous and -butanol fractions. Additionally, artificially fermented BCP has been evaluated against IAV (H1N1).

Metabolic Fingerprinting of Different Sideritis Taxa Infusions and Their Neurogenic Activity.

Over the last years, extracts were shown to improve memory. However, their potential to promote the generation of new neurons, starting with the neuronal differentiation of neural stem cells, remains unexplored. Therefore, the present study aimed to evaluate the neurogenic effects of different infusions in neural stem and precursor cells and their impact on cell viability.

Bio-Actives from Natural Products with Potential Cardioprotective Properties: Isolation, Identification, and Pharmacological Actions of Apigenin, Quercetin, and Silibinin.

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. As a result, pharmaceutical and non-pharmaceutical interventions modifying risk factors for CVDs are a top priority of scientific research. Non-pharmaceutical therapeutical approaches, including herbal supplements, have gained growing interest from researchers as part of the therapeutic strategies for primary or secondary prevention of CVDs.

Sideritis L. essential oils: A systematic review.

Essential oils are extensively used in the food, cosmetic, perfume, pharmaceutical, and agrochemical industries due to their aroma and pharmacological properties. The Lamiaceae family is mainly represented by widely well-known medicinal and aromatic plants that produce essential oil. Over the years, Sideritis L.

Phytochemical Characterization of Phitosia crocifolia, a Monotypic Representative of Greek Flora.

Within the large Compositae family, is considered a monotypic genus of the Greek flora, with its only species (Boiss. & Heldr.) Kamari & Greuter growing wild with limited distribution, exclusively on the mountains Taigetos and Parnonas in Peloponnese.

A Bio-Guided Screening for Antioxidant, Anti-Inflammatory and Hypolipidemic Potential Supported by Non-Targeted Metabolomic Analysis of spp.

This study was designed to evaluate the chemical fingerprints and the antioxidant, anti-inflammatory and hypolipidemic activity of selected species collected in Greece, namely, and (formerly known as ). For the phytochemical analyses, sample measurements were carried out by using nuclear magnetic resonance (NMR) spectroscopy and liquid chromatography coupled with mass spectrometry (LC-MS). Τhe extracts were evaluated both in vitro (radical scavenging activity: DPPH assay and total phenolic content: Folin-Ciocalteu) and in vivo (paw edema reduction and hypolipidemic activity: experimental mouse protocols).

Essential Oils-Composition and Bioactivities: An Update (2012-2022).

genus, considered to comprise over 500 species that exhibit cosmopolitan distribution, has attracted human interest since ancient times. The present review aims to provide and summarize the recent literature (2012-2022) on the essential oils of the title genus. Research articles were collected from various scientific databases such as PubMed, ScienceDirect, Reaxys, and Google Scholar.

Sustainable diets & medicinal aromatic plants in Greece: Perspectives towards climate change.

In recent years, climate change continuously concerns the scientific community about its effects on agrobiodiversity, food safety and human health. Remodeling to sustainable diets and lifestyles is proved to be the most radical need to tackle this grave phenomenon. The goals of this commentary are to present the Greek traditional Mediterranean diet as a principal sustainable diet, to emphasize the role of Medicinal and Aromatic Plants in Greece as indispensable components of this healthy dietary pattern, and to discuss the potential results of climate change at their phytochemical content.

Macrocyclic Diterpenoid Constituents of , an Endemic Spurge from Greece.

, an endemic spurge from Greece, was investigated for the occurrence of its diterpene constituents. Through continuous monitoring by H NMR, 22 diterpenoids were isolated, including 16 previously undescribed compounds (euphodeflexins A-P), which belong to the jatrophane, ingenane, segetane, and pepluane diterpene types. Their chemical structures were elucidated through a combination of HRESIMS, NMR spectroscopy, and X-ray data.

Cajamolides A-N: Cytotoxic and anti-inflammatory sesquiterpene lactones from Calea jamaicensis.

In the search for bioactive compounds from natural sources against cancer and inflammation, Calea jamaicensis (L.) L., a plant endemic to Panama, was investigated.

Polar constituents, biological effects and nutritional value of Boiss.

The present study focuses on the polar constituents and biological effects of the methanol extract and the infusion of wild Boiss. from Samos island (Greece), as well as on the nutritional and mineral contents of this plant. The total phenolic content and antioxidant activity were examined.

Prenylated Acylphloroglucinols from Hypericum jovis with Anti-inflammatory Potential.

Thirteen prenylated acylphloroglucinols (1: -13: ), including 2 previously undescribed compounds (1: ) and (2: ), were isolated from Their structures were elucidated by high-field NMR spectroscopy. The isolated prenylated acylphloroglucinols were evaluated for their anti-inflammatory effects through the reduction of the intercellular adhesion molecule 1 expression induced by TNF- in the human microvascular endothelial cells 1 cell line. Compounds 3, 5, 6, 8,: and 12: significantly reduced intercellular adhesion molecule 1 expression in a concentration-dependent manner with IC values of 16.

cytotoxic and anti-inflammatory activities of sesquiterpene lactones from (Coss.) Greuter.

In the pursuit of highly active specialized metabolites from endemic plants, (Coss.) Greuter, an endemic plant in Algeria and Tunisia, was investigated and afforded eleven sesquiterpene lactones (-). Cytotoxic evaluation of these compounds using the MTT assay on three human cancerous cell lines (HeLa, SK-MEL-28 and HepG2), revealed that isolates , and (IC ≤ 10 μM) could be potential anti-cancer drugs for cervical cancer according to the National Cancer Institute.