Publications by authors named "Helen Rushton"
Objectives: To determine whether caries experience in late childhood (aged 7-9 years) was predictive of adolescent obesity (ages 12-16 years) to inform the use of a common risk factor approach (CRFA) for prevention.
Methods: A cohort study was conducted in an area of North West England. Clinical assessment of caries took place using the same methodology at ages 7-9 years and 12-16 years.
Article Synopsis
- Transradial access for coronary procedures is linked to lower mortality and bleeding complications compared to transfemoral access.
- The study analyzed over 164,000 procedures, showing a 39% reduction in 30-day mortality with transradial access, influenced by the operator's experience and the volume of radial procedures they perform.
- Higher operator experience correlates with greater mortality risk reduction, stressing the importance of both total procedural volume and the frequency of transradial access among operators.
Background: Although covariate adjustment in the analysis of randomised trials can be beneficial, adjustment for continuous covariates is complicated by the fact that the association between covariate and outcome must be specified. Misspecification of this association can lead to reduced power, and potentially incorrect conclusions regarding treatment efficacy.
Methods: We compared several methods of adjustment to determine which is best when the association between covariate and outcome is unknown.
Background: Digital self-monitoring, particularly of weight, is increasingly prevalent. The associated data could be reused for clinical and research purposes.
Objective: The aim was to compare participants who use connected smart scale technologies with the general population and explore how use of smart scale technology affects, or is affected by, weight change.
Centrosome separation, critical for bipolar spindle formation and subsequent chromosome segregation during mitosis, occurs via distinct prophase and prometaphase pathways. Kinesin-5 (Eg5), a microtubule (MT) motor, pushes centrosomes apart during bipolar spindle assembly; its suppression results in monopolar spindles and mitotic arrest. Forces that antagonize Eg5 in prophase are unknown.
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