Vulvar ulcers in young females: a manifestation of aphthosis.

Study Objective: To examine the etiology, clinical course, and outcomes of non-sexually transmitted vulvar ulcers in young females.

Design: A prospective cohort study of subjects referred to a tertiary center who had active vulvar ulcers and no evidence of sexually transmitted infections were evaluated with a structured clinical and laboratory protocol and followed with visits or telephone calls.

Results: Twenty eligible subjects had a mean age of 14 years (range 10-19), and five were premenarchal.

Menstrual disorders in the college age female.

College-age young women frequently experience a variety of menstrual-related complaints, including dysmenorrheal, menorrhagia, irregular menses, and menstrual-related mood changes. These problems deserve careful evaluation; they may reflect normal ovulatory menstrual symptoms or be suggestive of significant pathology that can have a major impact on future reproductive and general health. The menstrual cycle is a vital sign whose normalcy suggests an overall good health and whose abnormality requires evaluation.

Unusual vulvar ulcerations in young adolescent females.

Study Objective: To review a series of young female patients who presented to the Cincinnati Children's Hospital Medical Center in Cincinnati, Ohio, from July of 1996 to November of 2001 with new, unexplained vulvar ulcerations, in order to elucidate common factors.

Design: Retrospective case series.

Setting: Cincinnati Children's Hospital Medical Center and its satellite offices.