Publications by authors named "Helen Queenan"
Rapid Assessment and Treatment In Decompensated Aortic Stenosis (ASTRID-AS study)- A pilot study.
Eur Heart J Qual Care Clin Outcomes
November 2023
Article Synopsis
- Acute decompensated aortic stenosis (ADAS) leads to higher mortality and longer hospital stays compared to stable aortic stenosis (AS), and this study aimed to reduce hospital length of stay (LoS) with a new treatment pathway.
- The ASTRID-AS pathway expedited the treatment process for ADAS patients, significantly cutting down the time to transcatheter aortic valve implantation (TAVI) and decreasing hospital LoS compared to a conventional approach.
- While the dedicated pathway saved an average of 13.4 bed days per patient and did not compromise safety, there was a slight increase in acute kidney injury or death within 30 days post-TAVI for the ASTRID-AS cohort.
In this report, we present a case of exacerbation of cold agglutinin syndrome (CAS) potentially due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. An 83-year-old female with a history of cold agglutinin hemolytic anemia presented with shortness of breath, productive cough, worsening orthopnea, darkening fingers and urine, and jaundice. Laboratory investigations found elevated white blood cells (WBC) and total bilirubin, severely low hemoglobin, and positive direct Coombs test.
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- A new study developed a CT aortic stiffness index (CTASI) that combines anatomical and physiological factors to assess aortic health, as aortic stiffness is a key predictor of cardiovascular risks.
- The study involved 80 patients who had invasive PWV measurements and CT scans, and 238 additional patients who only had CT scans, showing that CTASI closely correlated with invasive PWV results.
- CTASI proved to be a more accurate diagnostic tool for aortic stiffness and could predict 1-year mortality, suggesting it should be included in routine CT scans to enhance cardiovascular disease risk assessments.
Transcatheter aortic valve implantation in acute decompensated aortic stenosis.
Catheter Cardiovasc Interv
September 2020
Objectives: To assess the safety and efficacy of first-line transcatheter aortic valve implantation (TAVI) in patients presenting with acute decompensated aortic stenosis (ADAS).
Background: ADAS is common and is often treated medically or using balloon aortic valvuloplasty in the first instance. This temporizing measure results in suboptimal outcomes.