"None of Them Could Say They Ever Had Seen Them, but Only Had It from Others": Encounters with Animals in Eighteenth-Century Natural Histories of Greenland.

The pages of early modern natural histories expose the plasticity of the natural world, and the variegated nature of the encounter between human and animal in this period. Descriptions of the flora and fauna reflect this kind of negotiated encounter between the world that is seen, that which is heard about, and that which is constructed from the language of the sacred text of scripture. The natural histories of Greenland that form the basis of this analysis exemplify the complexity of human-animal encounters in this period, and the intersections that existed between natural and unnatural, written authority and personal testimony, and culture, belief, and ethnography in natural histories.

Permeability enhancing lipid-based co-solvent and SEDDS formulations of SQ641, an antimycobacterial agent.

Context: Tuberculosis (TB) is a common and often deadly infectious disease caused by strains of Mycobacteria. Development of new anti-tubercular drugs is essential to control the emergence and severity of multidrug-resistant TB.

Objective: The objective of this study was to develop an oral preclinical liquid formulation of SQ641 and to determine the permeability across rat intestinal tissue by Ussing chamber.

"It Was Never Good World Sence Minister Must Have Wyves": clerical celibacy, clerical marriage, and anticlericalism in Reformation England.

The impact of the Reformation was felt strongly in the nature and character of the priesthood, and in the function and reputation of the priest. A shift in the understanding of the priesthood was one of the most tangible manifestations of doctrinal change, evident in the physical arrangement of the church, in the language of the liturgy, and in the relaxation of the discipline of celibacy, which had for centuries bound priests in the Latin tradition to a life of perpetual continence. Clerical celibacy, and accusations of clerical incontinence, featured prominently in evangelical criticisms of the Catholic church and priesthood, which made a good deal of polemical capital out of the perceived relationship of the priest and the efficacy of his sacred function.

Influence of formulation factors on tablet formulations with liquid permeation enhancer using factorial design.

For a drug with low bioavailability, a matrix tablet with liquid permeation enhancer (Labrasol) was formulated. Factorial design was used to evaluate the effect of three formulation factors: drug percentage, polymer type (Methocel K100M or Eudragit L 100-55), and tablet binder percentage (Plasdone S-630) on tablet characteristics. Tablets were prepared by direct compression and characterized.

An Evaluation of Aerosol- and Liquid-Generated Silica Samples for Proficiency Analytical Testing.

SRI International has prepared dynamically generated silica samples since 1980 for the National Institute of Occupational Safety and Health (NIOSH) and the American Industrial Hygiene Association (AIHA) Proficiency Analytical Testing (PAT) programs. Aerosol-generated samples were developed in 1980 to more closely approximate real world samples and to improve intrabatch precision. Liquid-generated samples may provide tighter control limits, and this method has been reexamined as the generation procedure of choice.