Publications by authors named "Helen Kalampoka"
Comparison of Integrase Strand Transfer Inhibitors (INSTIs) and Protease-Boosted Inhibitors (PIs) on the Reduction in Chronic Immune Activation in a Virally Suppressed, Mainly Male Population Living with HIV (PLWH).
Thomas Nitsotolis Konstantinos G Kyriakoulis Anastasios Kollias Alexia Papalexandrou Helen Kalampoka
Medicina (Kaunas)
February 2024
Article Synopsis
- The study investigates the immunological and metabolic health of people living with HIV (PLWH) on combined antiretroviral therapy (cART) at Laiko General Hospital in Athens, focusing on potential health issues compared to the general population.
- It examines specific plasma markers and compares those receiving integrase strand transfer inhibitors (INSTIs) and protease inhibitors (PIs), finding higher IL-6 levels in the PIs group and normal-range LBP mostly in the INSTIs group.
- Overall, glucose, total cholesterol, and LDL cholesterol levels increased after viral suppression, particularly in the PIs group, although many other parameters showed no significant differences between the treatment groups.