Publications by authors named "Helen Gilbody"
Background: Limited knowledge exists about factors affecting parenteral iron response. A study was conducted to determine the factors influencing the erythropoietic response to parenteral iron in iron-deficient anaemic patients whose kidney function ranged from normal through all stages of chronic kidney disease (CKD) severity.
Methods: This retrospective cohort study included parenteral iron recipients who did not receive erythropoiesis-stimulating agents (ESA) between 2017 and 2019.
Article Synopsis
- This systematic review and meta-analysis aimed to compare the clinical and functional outcomes of side-to-end anastomosis versus colonic J-pouch (CJP) anastomosis after anterior resection for rectal cancer.
- The study included 1,125 patients from eight randomized controlled trials and two observational studies, assessing outcomes such as complications and bowel function.
- Results showed that while most parameters were similar between the two techniques, the side-to-end group had better anal resting pressure two years post-surgery, and further high-quality research is needed to evaluate long-term outcomes.
Background: Diversion of cerebrospinal fluid (CSF) is a common neurosurgical procedure for control of intracranial pressure (ICP) in the acute phase after traumatic brain injury (TBI), where medical management is insufficient. CSF can be drained via an external ventricular drain (EVD) or, in selected patients, via a lumbar (external lumbar drain [ELD]) drainage catheter. Considerable variability exists in neurosurgical practice on their use.
View Article and Find Full Text PDFSeveral studies have shown relationships between growth in early life and adult bone mass; in this article, we evaluate the relative contributions of pre- and postnatal factors to bone mass in the seventh decade. A total of 498 eight men and 468 women who were born in Hertfordshire during the period 1931-1939 and still living there were recruited. Detailed birth records were available.
View Article and Find Full Text PDFDoes sarcopenia originate in early life? Findings from the Hertfordshire cohort study.
J Gerontol A Biol Sci Med Sci
September 2004
Background: Sarcopenia is defined as the loss of skeletal muscle mass and strength with aging. Recent epidemiological studies have shown that men and women who grew less well in early life have lower muscle strength. Our objective was to investigate the relationship between birth weight, infant growth, and the development of sarcopenia.
View Article and Find Full Text PDFBackground: Size in early life is related to adult body mass index, and early environmental influences have been proposed to have lifelong consequences for obesity. However, body mass index also reflects fat-free mass, and few studies have examined the relation between size in early life and direct measures of body composition in older people.
Objective: We investigated the associations of birth weight and weight at 1 y of age with body composition in older men.