Publications by authors named "Helen Frazer"

Introduction: The evolving role of Artificial Intelligence (AI) in medicine, particularly in radiology and population-based breast cancer screening programs, offers potential accuracy gains and efficiency improvements. However, successful implementation requires understanding of healthcare workers' views on AI, which this study aims to explore within the Australian BreastScreen program.

Methods: An online survey was distributed to clinical staff involved in breast imaging, collecting responses from November 2022 to April 2023.

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Article Synopsis
  • AI readers show comparable effectiveness to individual radiologists in detecting breast cancer from mammograms, but fall short when matched against multi-reader systems used in screening programs in countries like Australia, Sweden, and the UK.
  • A study utilizing a high-quality dataset from Victoria, Australia, simulates five AI-integrated screening pathways, finding that AI functioning as a second reader or high-confidence filter can enhance screening outcomes, improving sensitivity and specificity by a small margin.
  • While automation bias negatively impacts performance in multi-reader situations, it can benefit single-reader cases; this research suggests promising strategies for integrating AI in mammography screening and highlights the need for further studies before clinical use.
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Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain malignant potential (B3 or BIRADS 3/4A lesions) who could safely be observed rather than being treated with surgical excision, with little impact on clinical practice. The primary reason for surgery is to rule out an upgrade to either ductal carcinoma in situ or invasive breast cancer, which occurs in up to 30% of patients. We hypothesised that the stromal immune microenvironment could indicate the presence of carcinoma associated with a ductal B3 lesion and that this could be detected in biopsies by counting lymphocytes as a predictive biomarker for upgrade.

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Article Synopsis
  • This study investigates how standardized test-set results can help identify breast-screening readers who improve cancer detection after training.
  • The research analyzes the test-set results of 41 participants alongside their annual cancer detection rates, using correlation tests and regression models to assess relationships between these metrics.
  • Findings show significant correlations, revealing that higher sensitivity leads to better detection rates, while increased specificity may not be as beneficial in improving performance.
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Methods to detect malignant lesions from screening mammograms are usually trained with fully annotated datasets, where images are labelled with the localisation and classification of cancerous lesions. However, real-world screening mammogram datasets commonly have a subset that is fully annotated and another subset that is weakly annotated with just the global classification (i.e.

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The deployment of automated deep-learning classifiers in clinical practice has the potential to streamline the diagnosis process and improve the diagnosis accuracy, but the acceptance of those classifiers relies on both their accuracy and interpretability. In general, accurate deep-learning classifiers provide little model interpretability, while interpretable models do not have competitive classification accuracy. In this paper, we introduce a new deep-learning diagnosis framework, called InterNRL, that is designed to be highly accurate and interpretable.

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Objective: Mammographic screening for breast cancer is an early use case for artificial intelligence (AI) in healthcare. This is an active area of research, mostly focused on the development and evaluation of individual algorithms. A growing normative literature argues that AI systems should reflect human values, but it is unclear what this requires in specific AI implementation scenarios.

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Mammography, Screening, Convolutional Neural Network (CNN) Published under a CC BY 4.0 license. See also the commentary by Cadrin-Chênevert in this issue.

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Background: Alongside the promise of improving clinical work, advances in healthcare artificial intelligence (AI) raise concerns about the risk of deskilling clinicians. This purpose of this study is to examine the issue of deskilling from the perspective of diverse group of professional stakeholders with knowledge and/or experiences in the development, deployment and regulation of healthcare AI.

Methods: We conducted qualitative, semi-structured interviews with 72 professionals with AI expertise and/or professional or clinical expertise who were involved in development, deployment and/or regulation of healthcare AI.

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There is limited research on the psychological wellbeing of female first responders (FRs) and therefore we explore potential indicators of burnout, psychological distress and post-traumatic stress disorder among Australian female FRs. We conducted an online health survey among Australian female FRs (fire, police, paramedical, aeromedical, remote area and other e.g.

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The application of artificial intelligence, and in particular machine learning, to the practice of radiology, is already impacting the quality of imaging care. It will increasingly do so in the future. Radiologists need to be aware of factors that govern the quality of these tools at the development, regulatory and clinical implementation stages in order to make judicious decisions about their use in daily practice.

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Introduction: This study aims to evaluate deep learning (DL)-based artificial intelligence (AI) techniques for detecting the presence of breast cancer on a digital mammogram image.

Methods: We evaluated several DL-based AI techniques that employ different approaches and backbone DL models and tested the effect on performance of using different data-processing strategies on a set of digital mammographic images with annotations of pathologically proven breast cancer.

Results: Our evaluation uses the area under curve (AUC) and accuracy (ACC) for performance measurement.

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Objective: The objective of this review is to produce a set of integrated findings of quantitative and qualitative evidence regarding workplace recruitment and retention factors (including departure) of female first responders to inform recommendations for policy and practice.

Introduction: Historically, first responder workforces such as police officers, firefighters, search and rescue personnel, medical technicians, and paramedics have been largely male dominated. Over the past few decades, however, there has been a steady increase in the number of women entering this field.

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Breast cancer care is a leading area for development of artificial intelligence (AI), with applications including screening and diagnosis, risk calculation, prognostication and clinical decision-support, management planning, and precision medicine. We review the ethical, legal and social implications of these developments. We consider the values encoded in algorithms, the need to evaluate outcomes, and issues of bias and transferability, data ownership, confidentiality and consent, and legal, moral and professional responsibility.

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Background: Breast Screen Reader Assessment Strategy (BREAST) is an innovative training and research program for radiologists in Australia and New Zealand. The aim of this study is to evaluate the efficacy of BREAST test sets in improving readers' performance in detecting cancers on mammograms.

Materials And Methods: Between 2011 and 2018, 50 radiologists (40 fellows, 10 registrars) completed three BREAST test sets and 17 radiologists completed four test sets.

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