Publications by authors named "Helen Claire O'Neill"
J Clin Pathol
December 2022
Article Synopsis
- PCOS is the most common reproductive endocrine disorder in women, yet the role of mitochondrial genetics in this condition is mostly unexplored.
- This study systematically reviewed existing literature to identify connections between mitochondrial DNA and PCOS, analyzing data from multiple databases.
- The findings revealed that women with PCOS have specific genetic variants in their mitochondrial genome and a lower mtDNA copy number, which may lead to cellular stress and damage, indicating a need for further research to clarify these associations.
