Initial presentation, management and follow-up data of 33 treated patients with hereditary tyrosinemia type 1 in the absence of newborn screening.

Hereditary tyrosinemia type 1 (HT1) is a rare autosomal recessive disorder of phenylalanine and tyrosine catabolism due to a deficiency of fumarylacetoacetate hydrolase. HT1 has a large clinical spectrum with acute forms presenting before six months of age, subacute forms with initial symptoms occurring between age 6 and 12 months, and chronic forms after 12 months of age. Without treatment, HT1 results in the accumulation of toxic metabolites leading to liver disease, proximal tubular dysfunction, and porphyria-like neurological crises.

Role play for genetic counseling learning: Value and students perceptions.

Background: Performing genetic counseling is one of the tasks of every paediatrician. This assumes prior training during the residency.

Aim: To assess the impact of role-play (RP) for training of paediatric residents in genetic counseling and participants' perception.

Patient-management Problem (PMP) for paediatrics learning: Value and students perceptions.

Background: The use of the pedagogic tool Patient-Management Problem (PMP) for medical teaching and evaluation remains limited in Tunisia.

Aim: to evaluate the value of PMP learning sessions in pediatrics and students' perception of the use of PMP for learning and evaluation.

Methods: We conducted a cross-sectional evaluative study in four pediatric departments in Tunis.

Correction to: Full title: peripheral venous catheter complications in children: predisposing factors in a multicenter prospective cohort study.

Following publication of the original article [1], one of the authors flagged that the title of the article was submitted (incorrectly) with "Full title:" at the beginning.

Peripheral venous catheter complications in children: predisposing factors in a multicenter prospective cohort study.

Background: Peripheral venous catheterization (PVC) is frequently used in children. This procedure is not free from potential complications. Our purpose was to identify the types and incidences of PVC complications in children and their predisposing factors in a developing country.