Cell-free DNA kinetics in response to muscle-damaging exercise: A drop jump study.

A significant increase in circulating cell-free DNA (cfDNA) occurs with physical exercise, which depends on the type of exertion and the duration. The aims of this study were as follows: (1) to investigate the time course of cfDNA and conventional markers of muscle damage from immediately after to 96 h after muscle-damaging exercise; and (2) to investigate the relationship between cfDNA and indicators of primary (low-frequency fatigue and maximal voluntary isometric contraction) and secondary (creatine kinase and delayed-onset muscle soreness) muscle damage in young healthy males. Fourteen participants (age, 22 ± 2 years; weight, 84.

Effect of sucralfate on peptic ulcer recurrence: a controlled double-blind multicenter study.

We entered 174 patients with healed duodenal ulcer and 77 with healed gastric ulcer into a double-blind, placebo-controlled, 6-month trial to investigate the efficacy of 1 g sucralfate twice daily in preventing ulcer recurrence. Endoscopy was performed after 6 months or earlier for symptoms compatible with ulcer disease. The relapse rate in the 126 patients with duodenal ulcer who could be evaluated for efficacy was 14/66 (21.

[5-Aminosalicylic acid in ulcerative colitis and Crohn's disease (author's transl)].

5-Aminosalicylic acid (5-ASA, 0.5 g t.i.

[Endoscopy by color television--a new technique? (author's transl)].

The routine endoscopic examination by color television is possible be new technical developments. For routine color television - endoscopy an efficient three-tube-camera should be used, directly attached to the endoscope. For demonstration purposes or to control technical proceedings in the field of operative endoscopy the one-tube-color television camera can be sufficient, even if there are difficulties also for the experienced examiner to read findings from the television screen.

Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease.

We studied the therapeutic efficacy of sulfasalazine and its metabolites sulfapyridine and 5-aminosalicylic acid in nine patients with Crohn's disease and in 23 patients with ulcerative colitis. In a randomized, controlled trial, we treated 11 patients for six weeks with 1 g of sulfasalazine three times a day, seven patients with 0.5 g of sulfapyridine three times a day, and 14 patients with 0.

[Effect of Gastropulgit on intragastric pH values. Telemetric study using the Heidelberg capsule].

Using a "quasi physiological" examination technique (Heidelberg capsule in free passage), the influence of Gastropulgit on the intragastral pH value was measured in comparison with 3 mEq/L sodium bicarbonate (NaHCO3), involving 147 patients. The following results were obtained. 1.

[Influence of (+)-cyanidanol-3 on acute hepatitis. Results of a double blind study (author's transl)].

42 cases of acute hepatitis diagnosed from 1970 to 1974 were reviewed retrospectively. The effect of (+)-Cyanidanol-3 on the course of acute hepatitis was controlled on 35 patients in a double blind study. During acute hepatitis, bed rest had an essential influence on the time needed to normalize the transaminases.

[Autoimmune hemolytic anemia with Donath-Landsteiner antibodies and antinuclear factors during the course of chronic-aggressive hepatitis].

With the onset of a remission phase of chronic aggressive hepatitis in a young female patient, two different auto-antibodies were found which had not previously been in evidence. These antibodies were identified as Donath-Landsteiner antibodies, the cause of a secondary auto-immune hemolytic anemia observed during this period, and anti-nuclear antibodies. Both antibodies were of the IgG class, both could be adsorbed onto the patient's own erythrocytes as well as P1-positive test erythrocytes, and both antibodies were present in the subsequent erythrocyte eluate.

[Endoscopic diagnosis of carcinoma in the operated stomach].

In 24 000 gastroscopies at 4 medical departments 705 subjects with gastric operations done more than 5 years before had been studied. 39 of 608 patients with Billroth II, 5 of 81 with Billroth I and 4 out of 15 with gastroenterostomy were found to be suffering from carcinoma of the gastric stump. The primary gastric operations were performed at a medium age of 40 years.

[Stomach motility and lyspafen].

Studies of motility of the stomach in 10 test-persons resulted in a significant reduction of motility after a 2-day period of perorally intake of Lyspafen. The active motoric substance is diffenoxin-hydrochloride. An addition of 0,025 mg Atropin sulfate could increase the effect.

[Examination using the gastro-camera and gastroscopy--confrontation and complementation].

Both the gastro-camera and gastroscopy are methods of examination dating back to the last century. Since 1955 examination with the gastro-camera has gained major importance in Japan. Not until the efficient gastroscopic instruments based on fiber optics and with extremely flexible points as well as advance view optical systems were developed large-scale, introduction esophageal gastro-bulboscopy in hospitals and in offices of specialists became possible.