Near-field luminescence measurements on GaInAsP/InP double heterostructures at room temperature.

Spatially resolved near-field luminescence spectroscopy was carried out on locally grown InP ridges, overgrown by a GaInAsP layer in metal organic molecular beam epitaxy. For free access to the quaternary layer the cleaved surface was investigated. Two different reflection scanning near-field microscopy setups were used.

[Use of "complementary methods" for experimental animal studies of digestion in the 18th and 19th centuries].

The use of complementary methods to animal experiments is very old. Spallanzani (1785) apparently was the first who used such methods in his studies on digestion. In the 19th century Eberle, Pappenheim, Purkyné and others used on their studies on the process of digestion artificial chyme.

[The origins of the gnotobiotic technic--Küster/Nuttall/Schottelius/ Thierfelder].

The first experiment to create germfree animals was done by NUTTALL and THIERFELDER in 1985. Later on, KUSTER (1912) published an apparatus which became the prototype for all following isolators. Another system was developed by SCHOTTELIUS in 1899, which became the prototype of the so-called "clean-room principle".

[Significance of procarbazine in the chemotherapy of Hodgkin's disease--a report of the Cooperative Therapy Study DAL-HD-85].

It was the objective of the DAL study HD-85 to examine the possibility of a reduction of chemotherapy, compared to the study HD-82 which had applied a combined treatment strategy resulting in a relapse rate of only 2.5% after 4 years, and a proportion of intercurrent deaths of 1.5%, in a total of 203 patients.

Prenatal toxic effects of STS 557. II. Investigation in rabbits--preliminary results.

The synthetic steroid STS 557 (17 alpha-cyanomethyl-17 beta-hydroxy-estra-4, 9-dien-3-one) was tested in gravid rabbits from days 5 to 25 p.c. It was the aim of the experiments to investigate any embryotoxic and/or teratogenic effect of STS 557.

Effect of quercetin on the course of mengo virus infection in immunodeficient and normal mice. A histologic study.

Quercetin protects mice from lethal Mengo M virus infection when given orally 12 and 1 hr before and 8, 24, 36, 48 and 56 hr after inoculation. No differences in the course of infection have been found between normal splenectomized or congenitally athymic mice. Likewise the effect of drug treatment was similar in all three models.

Experiences with a three step test scheme for embryotoxicity and teratogenicity.

Experiences with the three step teratological screening test for selection of teratogenic side effects are described. Step I: The prenatal examination of the foetuses may give indications of embryotoxicity, growth retardation and teratogenicity. Step II: The peri- and postnatal examination includes the duration of pregnancy, the delivery, the viability, the postnatal development and behaviour of the untreated offspring.

The immunosuppressive effect of beta-[1-phenyl-5-bis(beta-chloroethyl)-aminobenzimidazolyl-(2)]-DL-alanine (ZIMET 3164) on cell-mediated immunity in mice.

The potential immunosuppressive drug beta-[1-Phenyl-5-bis(beta-chloroethyl-5-amino-benzimidazolyl-(2)]-DL-alanine (ZIMET 3164) was tested for its effect on cell-mediated immunity. The models "skin grafting" and "contact hypersensitivity" were used. --The results showed a marked prolongation of the mean survival time of the skin grafts and also a high depression of the contact hypersensitivity (delayed hypersensitivity) to picryl chloride.

[Proof of sex-dependent effect of lambdamycin in mice].

The juvenile mouse is used as screening model to test feed additives for their potentially ergotropic effects. Weight development in 20-day old mice was found to be much more strongly influenced than in animals being 25 to 30 days old. The antibiotic lambdamycin inhibited weight gain in female mice, whilst males were promoted in weight development following lambdamycin application.

[Lambdamycin, an antibiotic from Streptomyces glaucoachromogenes Prauser strain MET 31118].

Lambdamycin-producing strains were detected by means of the BIP test method. The isolation technique and the physicochemical and biological properties of lambdamycin, an antibiotic produced by Streptomyces glaucoachromogenes, are described. Lambdamycin is a yellow-green pigment of the chromoglycoside type.