Publications by authors named "Heimiri Monnier"

Understanding cerebrospinal fluid (CSF) dynamics is crucial for elucidating the pathogenesis and diagnosis of neurodegenerative diseases. The primary mechanisms driving CSF oscillations remain a topic of debate. This study investigates whether cerebral blood volume displacement (CBV), modulated by breathing and cardiac activity, are the predominant drivers of CSF oscillations.

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Background: Understanding of the cerebrospinal fluid (CSF) circulation is essential for physiological studies and clinical diagnosis. Real-time phase contrast sequences (RT-PC) can quantify beat-to-beat CSF flow signals. However, the detailed effects of free-breathing on CSF parameters are not fully understood.

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Article Synopsis
  • The study investigates how free breathing impacts cerebral venous flow, which is important for understanding brain circulation and clinical practices.
  • Using two MRI techniques, CINE-PC and RT-PC, researchers measured blood flow in various brain veins of 28 healthy individuals to compare their effectiveness and assess breathing's effect on blood flow.
  • Results indicate that RT-PC is accurate in measuring cerebral venous flow and that breathing significantly alters flow rates, particularly in the jugular veins, providing new insights into cerebral circulation mechanisms.
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