Publications by authors named "Heikrujam Nilkanta Meitei"
Single nucleotide polymorphisms (SNPs) have been reported to influence the activity of specific genes involved with the innate immune response to Mycobacterium; hence, they are crucial in tuberculosis (TB) susceptibility studies. The study aimed to investigate the polymorphism in the NOS2A (Nitric oxide synthase 2A) gene and its association with susceptibility to TB in the Manipuri population of northeast India. This case-control study includes 495 subjects- 220 TB patients and 275 control individuals.
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- The study explores the neuroprotective effects of methanol extracts from two edible medicinal plants, Salix tetrasperma and Plantago asiatica, against rotenone-induced neurotoxicity in SH-SY5Y cells.
- Both plant extracts demonstrated antioxidant properties by reducing oxidative stress and improving survival of neurons affected by rotenone through various assays.
- LC-QTOF-MS analysis identified compounds with neuroprotective potential, suggesting these plants could be valuable sources for developing herbal nutraceuticals aimed at treating neurodegenerative diseases, such as Parkinson's.
Ethnopharmacological Relevance: Alternanthera sessilis (L.) R. Br.
View Article and Find Full Text PDFBackground: Anti-tuberculosis drug-induced liver injury (AT-DILI) is one of the most common side effects in TB patients during treatment. The prime cause of liver injury during TB treatment is reported to be isoniazid and its metabolites. Different factors influenced the development of AT-DILI, and genetic factors are one of the major factors.
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