Publications by authors named "Heike Kneifel"
Article Synopsis
- The NORTHSTAR-CA study investigates the effects of 1-Hz rTMS combined with speech-language therapy on naming recovery in both subacute and chronic post-stroke aphasia patients, aiming to compare their effectiveness.
- A total of 67 patients participated, receiving either rTMS or sham stimulation for 10 days, with significant improvements in language outcomes observed across groups; however, only subacute patients showed notable gains in naming recovery from rTMS.
- The findings suggest that rTMS enhances language recovery in the subacute phase post-stroke, highlighting a critical window for intervention, although further research is needed to confirm these results in a larger cohort.
Introduction: Non-invasive brain stimulation (NIBS) with speech therapy might improve recovery from post-stroke aphasia. This three-armed sham-controlled blinded prospective proof-of-concept study tested 1 Hz subthreshold repetitive transcranial magnetic stimulation (rTMS) and 2-mA cathodal transcranial direct current stimulation (ctDCS) on the right pars triangularis in subacute post-stroke aphasia.
Patients And Methods: Sixty-three patients with left middle cerebral artery infarcts were recruited in five hospitals (Canada/United States/Germany, 01-2014/03-2018) and randomized to receive rTMS ( = 20), ctDCS ( = 24) or sham stimulation ( = 19) with ST for 10 days.