Publications by authors named "Heidi Wolters"
Purpose: Primary radiochemotherapy (RCT) constitutes the standard of care for early- and advanced-stage anal carcinoma. This retrospective study investigates the impact of dose escalation on colostomy-free survival (CFS), overall survival (OS), locoregional control (LRC), progression-free survival (PFS), and acute and late toxicities in patients with squamous cell anal cancer.
Methods: Considered were the outcomes of 87 patients with anal cancer treated with radiation/RCT between May 2004 and January 2020 at our institution.
Purpose: The aim of the study is to evaluate treatment-related acute and late eye toxicity associated with radiation therapy in childhood and adolescence as correlated with RT (radiotherapy) doses.
Methods: From 2001 to 2016, a total of 1725 children and adolescents undergoing radiation therapy were prospectively documented in the Registry of the Evaluation of Side Effects after Radiotherapy in Childhood and Adolescence (RiSK). The RTOG/EORTC criteria were used to classify ocular acute and late effects.
Objective: The objective of this study was to assess the accuracy of Ga-PSMA-11 PET/MRI, F-PSMA-1007 PET/CT, Ga-PSMA-11 PET/CT, and multiparametric (mp)MRI for the delineating of dominant intraprostatic lesions (IPL).
Materials And Methods: 35 patients with organ-confined prostate cancer who were assigned to definitive radiotherapy (RT) were divided into three groups based on imaging techniques: Ga-PSMA-PET/MRI (n = 9), F-PSMA-PET/CT (n = 16) and Ga-PSMA-PET/CT (n = 10). All patients without PSMA-PET/MRI received an additional mpMRI.
Impact of Whole Lung Irradiation on Survival Outcome in Patients With Lung Relapsed Ewing Sarcoma.
Int J Radiat Oncol Biol Phys
November 2018
Article Synopsis
- A retrospective study analyzed survival outcomes in 136 patients with isolated pulmonary relapse of Ewing sarcoma, focusing on the effects of whole lung irradiation (WLI) combined with second-line chemotherapy.
- The results indicated that patients who received WLI showed significantly better 3-year progression-free survival (36% vs. 14%) and overall survival (47% vs. 33%) compared to those who did not.
- Although WLI did not drastically improve overall survival rates, it did not cause severe lung toxicity, and factors like primary tumor site and response to chemotherapy were relevant for predicting patient outcomes.
Purpose: To ascertain the optimal radiation technique and radiation position for the neoadjuvant radiotherapy of patients with rectal cancer.
Materials And Methods: Treatment plans with similar dose objectives were generated for 20 selected patients. Dosimetric comparison was performed between prone and supine positions and between different radiation techniques.
Purpose: To analyze the incidence and degree of sensorineural hearing loss (SNHL) resulting from different radiation techniques, fractionation dose, mean cochlear radiation dose (D), and total cisplatin dose.
Material And Methods: In all, 29 children with medulloblastoma (58 ears) with subclinical pretreatment hearing thresholds participated. Radiotherapy (RT) and cisplatin had been applied sequentially according to the HIT MED Guidance.