MMNTP-a new tailor-made modular derivatization agent for the selective determination of isocyanates and diisocyanates.

The synthesis of a new tailor-made derivatization agent for the selective determination of (di)isocyanates is presented. Starting from cyanuric chloride, the reagent 4-methoxy-6-(4-methoxy-1-naphthyl)-1,3,5-triazine-2-(1-piperazine)(MMNTP) is synthesized by subsequent substitution of the three chlorine atoms. This new derivatization agent and the five urea derivatives of phenylisocyanate (PI), hexamethylene-diisocyanate (HDI), toluene-2,4-diisocyanate (2,4-TDI), toluene-2,6-diisocyanate (2,6-TDI) and methylenebisphenyl-4,4-diisocyanate (MDI) show good spectroscopic properties with small compound-to-compound variabilities (RSD([epsilon])= 5.