Association of and Polymorphisms with Juvenile Idiopathic Arthritis in Finnish Children.

To analyze the role of interleukin and polymorphisms in susceptibility to juvenile idiopathic arthritis (JIA), 98 Finnish children and adolescents with JIA were studied. Data from the 1000 Genomes Project, consisting of 99 healthy Finns, served as the controls. The patients were analyzed for four and three gene-promoter polymorphisms, and the serum IL-17A, IL-17F, IL-10, and IL-6 levels were determined.

Incidence of juvenile idiopathic arthritis in Finland, 2000-2020.

Objective: Previous epidemiological data of JIA in Finland are from the turn of the millennium. We aimed to determine the recent annual incidence of JIA in several consecutive years in Finland and to explore the differences in incidence between sexes, age groups and regions.

Methods: We analysed all children <16 years of age who met the ILAR classification criteria for JIA.