Publications by authors named "Heidi Nurmonen"
Article Synopsis
- The study explores the relationship between pre-eclampsia and saccular intracranial aneurysms (sIAs), focusing on female patients, their relatives, and matched controls, to assess the prevalence of pre-eclampsia in these groups.
- It analyzed data from 265 female sIA patients, their female relatives, and a control group, revealing a higher prevalence of pre-eclampsia in sIA patients (11%) compared to matched controls (6%).
- The findings indicate that pre-eclampsia is more common among sIA patients, with familial occurrences observed in seven families, suggesting a need for further research into how pre-eclampsia may increase the risk of sIA rupture.
Article Synopsis
- - The study aimed to investigate the occurrence of pre-eclampsia, gestational hypertension, chronic hypertension, and gestational diabetes in pregnant women with saccular intracranial aneurysms (sIAs).
- - Researchers analyzed medical records of 169 patients with sIA from 1990 to 2015, finding that 13% had pre-eclampsia and 19% experienced other hypertensive issues, compared to 5% and 10% in matched controls, respectively.
- - The findings suggest pre-eclampsia is more common in women with sIA, and those with pre-eclampsia tended to have irregularly shaped aneurysms, indicating a need for further research on
Objective: The authors set out to study whether autosomal dominant polycystic kidney disease (ADPKD), an established risk factor for intracranial aneurysms (IAs), affects the acute course and long-term outcome of aneurysmal subarachnoid hemorrhage (aSAH).
Methods: The outcomes of 32 ADPKD patients with aSAH between 1980 and 2015 (median age 43 years; 50% women) were compared with 160 matched (age, sex, and year of aSAH) non-ADPKD aSAH patients in the prospectively collected Kuopio Intracranial Aneurysm Patient and Family Database.
Results: At 12 months, 75% of the aSAH patients with ADPKD versus 71% of the matched-control aSAH patients without ADPKD had good outcomes (Glasgow Outcome Scale score 4 or 5).
Background Varying degrees of co-occurrence of intracranial aneurysms (IA) and aortic aneurysms (AA) have been reported. We sought to compare the risk for AA in fusiform intracranial aneurysms (fIA) and saccular intracranial aneurysms (sIA) disease and evaluate possible genetic connection between the fIA disease and AAs. Additionally, the characteristics and aneurysms of the fIA and sIA patients were compared.
View Article and Find Full Text PDFBackground And Purpose: To study the penetrance of saccular intracranial aneurysm (IA) disease in children when both parents carry the disease.
Patients And Methods: The Kuopio IA Patient and Family Database includes all 4,411 IA patients admitted to the Kuopio University Hospital from its defined Eastern Finnish catchment population since 1980. We fused IA database with hospital diagnoses for IA patients and their 46,021 relatives from a national registry to identify couples concordant for IA disease.
Objective: To define the association of autosomal dominant polycystic kidney disease (ADPKD) with the characteristics of aneurysmal subarachnoid hemorrhage (aSAH) and unruptured intracranial aneurysm (IA) disease.
Methods: We fused data from the Kuopio Intracranial Aneurysm database (n = 4,436 IA patients) and Finnish nationwide registries into a population-based series of 53 IA patients with ADPKD to compare the aneurysm- and patient-specific characteristics of IA disease in ADPKD and in the general IA population, and to identify risks for de novo IA formation.
Results: In total, there were 33 patients with ADPKD with aSAH and 20 patients with ADPKD with unruptured IAs.