Development of In Vitro Assays with the Canine Hookworm and Assessment of Natural Plant Products for Anti-Parasitic Activity.

Enteric helminth infection is an increasing concern in companion animals due to reports of resistance to commonly used anthelmintic drugs. Thus, the assessment of new therapeutic options such as bioactive dietary additives is of high importance. Here, we adapted egg hatch, larval migration, and larval motility assays to screen extracts of several natural ingredients against the canine hookworm , a prevalent parasite of dogs in northern Europe.