Publications by authors named "Heguo Luo"
Article Synopsis
- Ciprofol is a new sedative anesthetic that shows promise for older adults, particularly in reducing hypotension during anesthesia induction compared to propofol.
- In a study of 117 older adults, ciprofol resulted in a lower incidence of hypotension (26.3%) compared to propofol (48.3%).
- Patients receiving ciprofol also reported less injection pain and maintained stable blood pressure levels while achieving successful anesthesia induction in both groups.
Background: Isoflurane can significantly induce inflammation in children without surgical stress. The toll-like receptor 4 (TLR4) is closely related to noninfectious inflammation in the brain.
Objectives: To investigate the role of TLR4-small interfering RNA (siRNA) in learning and memory impairment in young mice induced by isoflurane.
Aim: Diabetes is a high-risk factor for neurocognitive dysfunction. Diabetic acute hyperglycaemia accompanied by high osmotic pressure can induce immune cell dysfunction, but its mechanism of action in brain microglia remains unclear. This study aimed to evaluate the role of the mechanically sensitive ion channel Piezo1 in the dysfunction of microglia in acute hyperglycaemia.
View Article and Find Full Text PDFBackground: Although ultrasound-guided transversus abdominis plane block (TAPB) is widely used in multimodal analgesia after cesarean delivery (CD), the complications of TAPB during analgesia after CD have rarely been reported.
Methods: A total of 84 cases of CD were randomly assigned to either a ropivacaine group (R group) or ropivacaine + dexamethasone group (RD group) in this double-blind trial. The pain site and pain degree at rest and during activity at 2 h, 6 h, 10 h, 12 h, 14 h, 16 h, 20 h, and 24 h after maternal surgery were recorded.
The effect of hypercapnic acidosis preconditioning on rabbit myocardium.
J Huazhong Univ Sci Technolog Med Sci
December 2008
This study observed the protective effect of hypercapnic acidosis preconditioning on rabbit heart suffered from ischemia-reperfusion injury. Hypercapnic acidosis was established in animals with mechanical hypoventilation before ischemia-reperfusion. Thirty-two rabbits were randomly divided into 4 groups, with each having 8 animals in term of the degree of acidification: hypercapnic acidosis group A (group A), hypercapnic acidosis group B (group B), hypercapnic acidosis group C (group C), ischemia and reperfusion group (group IR).
View Article and Find Full Text PDF[Effects of ulinastatin on cerebral inflammatory response during cardiopulmonary bypass].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2005
Objective: To investigate the effects of ulinastatin (UTI) on cerebral inflammatory response during cardiopulmonary bypass (CPB).
Methods: Twenty-four NYHA II-III patients (13 males and 11 females) aged 23-45 years, undergoing elective cardiac valve replacement under hypothermic CPB were randomly divided into 2 groups: ulinastatin group (Group U, n=12) and control group (Group C, n=12). In group U, UTI (1.
[Effect of ulinastatin on human blood coagulation and platelet aggregation in orthopaedic surgery].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2004
Objective: To investigate the effect of ulinastatin (UTI) on human blood coagulation and platelet aggregation in orthopaedic surgery.
Methods: Thirty ASA I-II patients without blood dyscrasia and blood coagulation obstacle were randomly divided into two groups: Group I (UTI group, n=15) in which patients received UTI 5000 U/kg, and Group II (control group, n=15) in which patients received NS 100 ml. PT, TT, APTT, IB, INR and PAG1, PAG5, and PAGM were measured at 3 points: pre-infusion (T0), 1 hour after the infusion (T1), and 2 hours after the infusion (T2).