Publications by authors named "Hege Marie Hanssen"
Introduction: The observed alteration of the intestinal microbiota in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and the effect of transferring a healthy gut flora from a faecal donor using a faecal microbiota transplantation (FMT) will be explored in this trial.
Methods And Analysis: This is a protocol for a randomised, double-blind, placebo-controlled, parallel-group, single-centre trial, with 12 months follow-up. 80 participants will be included and randomised (1:1:2) to either donor FMT (from two different donors) or placebo (autologous FMT).
Introduction: Obesity is one of the main threats to public health in western countries and increases the risk of several diseases, overall morbidity and mortality. Sustained weight loss will reduce risk factors and improve several obesity comorbidities. Options are conservative treatment such as lifestyle changes, bariatric surgery or medications.
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- Fecal microbiota transplantation (FMT) is a promising treatment for recurrent Clostridioides difficile infections, and understanding its distribution in the colon through different delivery methods is crucial.
- In a study with eight participants, contrast fluid was administered via colonoscopy and enema to compare how well it reached different parts of the colon, revealing that colonoscopy effectively reaches the cecum, while enemas provide more variable results.
- Results indicated that while enema delivery does reach the proximal colon, colonoscopy remains the most reliable method, highlighting the need for further research on how the distribution of FMT relates to its effectiveness in treating infections.