Publications by authors named "Heerim Yeo"
L. has exhibited various pharmacological effects, yet its anticancer activities against colorectal cancer (CRC) and underlying molecular mechanisms remain unclear. This study investigated the anticancer properties of an ethanol extract of L.
View Article and Find Full Text PDFBojungikki-Tang (BJIKT) is traditionally used to enhance digestive function and immunity. It has gained attention as a supplement to chemotherapy or targeted therapy owing to its immune-boosting properties. This study aimed to evaluate the synergistic anti-tumor effects of BJIKT in combination with pembrolizumab in a preclinical model.
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- - Targeted therapies using EGFR inhibitors have significantly improved the survival and quality of life for patients with EGFR-mutant lung adenocarcinoma, yet many still face resistance to these treatments.
- - The study investigates the potential of combining Paeoniae Radix (PR) with first-generation EGFR-TKIs (erlotinib and gefitinib) to counteract this resistance by targeting specific gene signatures related to the resistance mechanism.
- - Results showed that this combination therapy enhanced drug effectiveness by suppressing the Aurora B pathway and promoting cell death in LUAD cells, suggesting a promising natural approach to overcoming drug resistance in lung cancer treatment.