Publications by authors named "Heekyung Cho"
Article Synopsis
- Orthohantavirus hantanense is a significant public health threat in Eurasia, causing hemorrhagic fever; while the primary causing agent in the Republic of Korea (ROK) is the Hantaan virus, the Amur virus (AMRV) may also be transmitted to humans from rodents in China and Russia.
- A study of rodents in Gangwon Province from 2015 to 2018 found that 16.1% tested positive for the Soochong virus (SOOV), with complete genomic sequencing revealing five novel whole-genome sequences, highlighting particular regions in Hongcheon-gun and Pyeongchang-gun.
- Phylogenetic analysis showed distinct evolutionary patterns between
Article Synopsis
- Hepatitis E virus (HEV), specifically the rat variant HEV-C1, is an emerging zoonotic threat, previously underestimated as a cause of human hepatitis due to lack of research on transmission and risk factors.
- A study in South Korea identified an HEV-C1 RNA prevalence of 4.4% among 186 wild Norway rats, highlighting the virus's presence in urban areas.
- Phylogenetic analysis showed that Korean HEV-C1 is genetically distinct from strains found in other countries, emphasizing the need for increased awareness and understanding of this virus among healthcare professionals.
Article Synopsis
- * During 2017-2018, a study found a 12.4% serological prevalence of Hantaan orthohantavirus (HTNV) in small mammals, alongside the development of a rapid diagnostic method using a nanopore-based Flongle chip that can detect HTNV in rodent samples within 3 hours.
- * The study also achieved high-resolution sequencing of HTNV genomes from rodents, revealing insights into the virus's evolutionary dynamics and supporting better surveillance and potential prevention strategies in
Whole-genome sequencing provides a robust platform for investigating the epidemiology and transmission of emerging viruses. Oxford Nanopore Technologies allows for real-time viral sequencing on a local laptop system for point-of-care testing. (Seoul virus, SEOV), harbored by and , causes mild hemorrhagic fever with renal syndrome and poses an important threat to public health worldwide.
View Article and Find Full Text PDFSpinal cord injury (SCI) causes not only loss of sensory and motor function below the level of injury but also chronic pain, which is difficult and challenging of the treatment. Repetitive transcranial magnetic stimulation (rTMS) to the motor cortex, of non-invasive therapeutic methods, has the motor and sensory consequences and modulates pain in SCI-patients. In the present study, we studied the effectiveness of rTMS and the relationship between the modulation of pain and the changes of neuroglial expression in the spinal cord using a rat SCI-induced pain model.
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