Publications by authors named "Hee Y Lee"

This study examined relationships among caregiver burden, depressive symptoms, and key processes related to psychological flexibility (experiential avoidance, cognitive fusion, values-driven actions, and mindfulness) in 157 family caregivers of individuals with dementia in the United States. Path analyses were used. Participants' mean age was 59.

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Purpose: Korean immigrant families are growing in the Southern United States (U.S), an area where culturally specific resources can be limited. Korean immigrant families encounter distress in navigating the American culture, but cultural stigma impedes discussion within the family.

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This national population-based study aimed to assess the cumulative burden of non-alcoholic fatty liver disease (NAFLD) measured via the fatty liver index (FLI) and its association with kidney cancer risk in young men aged 20-39. : Using the Korean National Health Insurance Service database, we examined a cohort of 1,007,906 men (age 20-39) who underwent four consecutive annual check-ups from 2009 to 2012. The FLI, calculated from body mass index values, waist circumference, triglyceride levels, and gamma-glutamyl transferase levels, was used to quantify the cumulative burden of NAFLD (FLI ≥ 60).

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Prior research has linked the social determinants of health, such as food insecurity and housing instability, to experiences of interpersonal violence. However, little is known about how the social determinants of health are related to the risk for interpersonal violence among Black Americans living in rural, high-poverty communities in the Deep South. The intersection of rurality, racialized identity, and economic hardship makes this population particularly vulnerable to interpersonal violence, yet this population is underrepresented in the literature.

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The daily Internet use among older adults has increased. This study examines how Internet usage affects depressive symptoms among older adults, focusing on gender differences. Using data from the 2015 National Health and Aging Trends Study ( = 6380), weighted multinomial logistic regression analysis was conducted.

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Isoflavone-enriched soybean leaves (IESLs) were processed for drying, steaming, and fermentation, and bioactive compounds and biological activities were analyzed. During food processing, the content of fatty acids, water-soluble vitamins, total phenolics, total flavonoids, and isoflavone-aglycones increased from dried IESLs (DrIESLs) to fermented IESLs (FeIESLs). Especially, oleic acid (53.

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Introduction: Unmet medical needs in rural areas are of grave concern in the U.S. With the advent of digital technologies, the Internet has become a critical means for accessing essential health information.

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  • This study analyzed the nutrients and antioxidant activities of different ratios (0%, 2.5%, 5%, and 10%) of mountain-cultivated ginseng (MCG) fermented with specific microorganisms.
  • It found that fermentation altered the content of isoflavones and ginsenosides, generally decreasing certain types while increasing others, particularly beneficial compounds like ginsenoside Rg3 and compound K.
  • The results suggest that higher ratios of MCG enhance the overall quality, antioxidant properties, and potential health benefits, making it valuable for food and pharmaceutical uses.
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This study examines how functional disability worsens among older adults exposed to extreme heat, particularly those socially isolated. Analyzing data from over 35,000 older adults aged 50 or older from the Health and Retirement Study from 1996-2018, this study found that more frequent exposure to extreme heat is associated with an increase in the number of instrumental activities of daily living (IADL) that older adults find difficulty in performing over time. This heat-related disability progression is greater among those living alone and not working.

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  • Incomplete resection rates vary among endoscopists, making it important to evaluate different removal techniques for small colorectal polyps.
  • This study compared the effectiveness and safety of cold snare endoscopic mucosal resection (CS-EMR) and hot snare endoscopic mucosal resection (HS-EMR) on polyps sized 6-9 mm.
  • Results showed that CS-EMR had a 0% rate of residual adenomas and similar efficacy in resection compared to HS-EMR, suggesting CS-EMR can be a standard method for removing small colorectal polyps.
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  • This study investigates how extreme heat affects cognitive function in older adults, focusing on risk and protective factors using a social-ecological model.
  • Data from the Health and Retirement Study (1996-2016) was analyzed to see how extreme heat days impact fluid and crystallized intelligence scores in older adults aged 50 and up, considering factors like education and social interaction.
  • Results indicated that extreme heat negatively impacted fluid intelligence, with educational level, physical activity, and social engagement helping to mitigate these effects, suggesting the need for policies to enhance resilience in older adults during heat events.
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  • - This study examined how solid-state fermentation with various fungi affects the nutritional components, isoflavones, and antioxidant activities of Apios americana Medikus (AAM), highlighting significant increases in fatty acid and amino acid content post-fermentation.
  • - The fermentation process, particularly with the fungus Monascus purpureus, resulted in a remarkable increase in total fatty acids (up to 26.3 times) and improved mineral contents, demonstrating notable nutritional enhancement.
  • - Isoflavone glycosides in unfermented AAM were converted to more beneficial aglycone forms during fermentation, leading to higher total phenolic and flavonoid contents, which suggests that fermented AAM could be a valuable ingredient for food and medicinal
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This study was the first to document the fluctuations of nutritional constituents, antioxidant capacities, and physicochemical characteristics during the aging processes of red ginseng sprouts (RGS) and black ginseng sprouts (BGS) from dried ginseng sprouts (DGS). Total ginsenoside levels differed with 54.72 (DGS) → 57.

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Objective: Although diabetes is one of the leading causes of death among Korean Americans, the levels and predictors of diabetes knowledge in this group have not been sufficiently reported. This study aimed to (1) describe the level of diabetes knowledge of Korean immigrant women in the U.S.

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Background And Aims: Colorectal endoscopic submucosal dissection (ESD) is challenging despite its usefulness. Underwater ESD (UESD) provides better traction and a clearer view of the submucosal layer than conventional ESD (CESD). This study compared the efficiency of UESD and CESD for large (20-50 mm) laterally spreading tumors (LSTs).

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  • * The main source of this thermogenesis is the exothermic oxygen reduction reaction, which generates heat that can be transferred to other cellular organelles, including the nucleus.
  • * This heat activates the heat shock response in the nucleus, including the formation of stress granules and the relocation of heat shock factor 1 (HSF1), leading to increased gene expression that helps cells cope with thermal stress.
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Introduction: A Monoplace hyperbaric chamber delivers oxygen to the patient's tissues through breathing. Gas monitoring inside the chamber is important because oxygen (O) is consumed, and carbon dioxide (CO) is increased because treatment is performed in a closed volume. This study aimed to advance the safety and efficacy of the monoplace hyperbaric chamber (MHC) through mechanical improvement in a gas monitoring system (GMS).

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The current research was the first to prove the existence of fluctuations in the metabolite constituents and antioxidant properties in different organs (leaves, stems, and roots) of the mountain-cultivated ginseng (MCG) plant during a two-month maturation period. Four metabolites, including fatty acids, amino acids, ginsenosides, and phenolic phytochemicals, exhibited considerable differences in organs and maturation times with the following order: leaves > stems > roots. The predominant metabolite contents were found in leaves, with fatty acid (1057.

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Novel clinical trial designs are conducted in the precision medicine era. This study aimed to evaluate biomarker-driven, adaptive phase II trials in precision oncology, focusing on infrastructure, efficacy, and safety. We systematically reviewed and analyzed the target studies.

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Background: Hodgkin lymphoma (HL) survivors who received chest radiotherapy are at risk for breast cancer and cardiovascular disease, but screening adherence is low. We assessed the acceptability/feasibility of a web-based educational intervention and its impact on knowledge of health risks and screening.

Methods: HL survivors were randomized to either an interactive online educational intervention or handouts only.

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  • Ecological momentary assessment (EMA) is a method that helps capture the real-time experiences of family caregivers, particularly for those caring for adults with chronic conditions.
  • A systematic review identified 12 studies focused mainly on caregivers of individuals with Alzheimer's or dementia, revealing a 75% average compliance rate, which is below the ideal standard.
  • The review highlighted that while EMA is a feasible approach for collecting caregiver data, many studies lack essential information on caregivers' daily activities and emotional experiences, indicating a need for further research in this area.
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Health literacy is associated with health behaviors and outcomes. Using Andersen's Behavioral Model of Health Services Use, this study examined the role of limited English proficiency (LEP) and social support for the health literacy of Korean American immigrant women, one of the most affected groups by LEP. Researchers surveyed 232 Korean American immigrant women in a metro area in a Southeastern state, U.

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Bridging the healthcare access gap and addressing COVID-19 vaccine hesitancy among rural-dwelling Black American adults residing in the Deep South require involvement of faith-based leaders in the community. This study explored perceived barriers and resources to meeting community needs, including vaccination, during the COVID-19 pandemic as reported by 17 Black American church leaders in the rural West Alabama Black Belt geographic region in May 2022. The main themes that emerged included (1) attending to community impact of COVID-19 illness and death; (2) maximizing health literacy and diminishing vaccine hesitancy through engaging in preventive health practices and sharing public health information; (3) addressing challenges created or exacerbated by COVID-19, including reduction in in-person attendance (particularly among adolescents and young adults), limited access to and literacy with technology, and political perceptions influencing engagement in preventive health behaviors; (4) maximizing technological solutions to increase attendance in the church; and (5) engaging in solution-focused and innovative initiatives to meet the identified needs in the congregation and community.

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Introduction: This study investigated the role of renal-intestinal crosstalk in the transition from acute kidney injury (AKI) to chronic kidney disease (CKD) in elderly individuals.

Methods: Using young and aged mice, we induced bilateral ischemia-reperfusion injury (IRI) and compared intestinal and kidney inflammation over 28 days. To determine the role of the microbiome in gut-kidney crosstalk, we analyzed the microbiome of fecal samples of the young vs.

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  • Researchers developed high isoflavone-enriched soy leaves (IESLs) using the chemical inducer ethephon at varying concentrations (0, 150, and 300 μg/mL) to enhance the nutritional properties of underutilized soy leaves.
  • The study found that, while proximate composition and fatty acids showed minimal differences, free amino acids and water-soluble vitamins increased significantly with higher ethephon concentrations, with isoflavone levels rising dramatically.
  • The findings suggest that soy leaves treated with ethephon could serve as valuable ingredients for functional foods, cosmetics, and natural medicinal products due to their increased nutritional components.
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