Phase 3 Efficacy Trial of Modified Vaccinia Ankara as a Vaccine against Smallpox.

Background: Many countries have stockpiled vaccines because of concerns about the reemergence of smallpox. Traditional smallpox vaccines are based on replicating vaccinia viruses; these vaccines have considerable side effects.

Methods: To evaluate the efficacy of modified vaccinia Ankara (MVA) as a potential smallpox vaccine, we randomly assigned 440 participants to receive two doses of MVA followed by one dose of the established replicating-vaccinia vaccine ACAM2000 (the MVA group) or to receive one dose of ACAM2000 (the ACAM2000-only group).

Association of temperature and historical dynamics of malaria in the Republic of Korea, including reemergence in 1993.

Plasmodium vivax malaria reemerged in the Republic of Korea in 1993 after it had been declared malaria free in 1979. Malaria rapidly increased and peaked in 2000 with 4,142 cases with lower but variable numbers of cases reported through 2011. We examined the association of regional climate trends over the Korean Peninsula relative to malaria cases in U.

Malaria in the Republic of Korea, 1993-2007. Variables related to re-emergence and persistence of Plasmodium vivax among Korean populations and U.S. forces in Korea.

Malaria was eradicated and the Republic of Korea (ROK) declared "malaria free" in 1979. However, in 1993, a temperate strain of vivax malaria, expressing both latent and nonlatent disease populations, re-emerged near the demilitarized zone (DMZ), rapidly spread to civilian sectors near the DMZ, and increased exponentially in ROK military, veteran, and civilian populations through 1998. Malaria among all ROK populations decreased 5-fold from a high of 4142 cases in 2000 to a low of 826 cases in 2004, before increasing again to 2180 cases by 2007.

Plasmodium vivax malaria among U.S. forces Korea in the Republic of Korea, 1993-2007.

Malaria is a significant health threat to U.S. combat forces that are deployed to malaria-endemic regions.

The war on severe acute respiratory syndrome: United States Forces Korea's campaign plan.

A mysterious new respiratory illness known as severe acute respiratory syndrome (SARS) has become the most perplexing infectious disease to emerge in the 21st century. From March to May 2003, it competed daily with the war in Iraq as the most sensational media event of the moment. U.

Medical needs of tsunami disaster refugee camps.

Background And Objectives: In response to the massive tsunami disaster in South Asia, two Korean medical relief teams provided emergency medical care in the southern coastal area of Sri Lanka. Their findings are reported here to provide a realistic picture of medical needs created by the tsunami disaster and to enable a better-prepared medical response to future disasters of this type.

Methods: All victims of the tsunami in the area of operation of the two medical relief teams were encouraged to receive medical care.

A preliminary investigation of early smoking initiation and nicotine dependence in Korean adults.

Background: Few studies have investigated the association between age at smoking initiation and Fagerström test for nicotine dependence (FTND) in adulthood. The goal of this study was to develop the Korean version of FTND (FTND-K) and to examine the relationship between age at smoking initiation and nicotine dependence.

Methods: This investigation used data from 268 current smokers who visited the Center for Cancer Prevention and Early Detection in the National Cancer Center, Korea.