Publications by authors named "Hedya Jemai"

Article Synopsis
  • Resveratrol (RSV) is a natural compound known for its health benefits and potential in treating various diseases, but its effectiveness is limited by poor physical properties like low solubility and stability.
  • Recent research focuses on enhancing RSV’s bioavailability by combining it with innovative materials such as nanoparticles, polymers, and bio-ceramics.
  • This review examines the latest advances in RSV applications, compares extraction methods, and highlights its therapeutic effects, while also addressing the need for further studies to confirm these benefits in clinical settings.
View Article and Find Full Text PDF

is a halophyte plant that has been used in traditional medicine for the treatment of scurvy, goiter, and hypertension. It is commercialized in Europe and Asia as fresh salads, pickled vegetables, green salt, or tea powder. This work is the first to assess the potential anti-obesity and anti-dyslipidemic effects of decocted extract (SADE).

View Article and Find Full Text PDF

Cadmium (Cd) is a harmful pollutant which mainly affects the liver and kidney. In this work, we investigated the hepatoprotective effects of olive leaf extract based on oleuropein against hepatic cadmium toxicity in mice. Three groups of animals were used: the first one served as the control (C); the second one received intraperitoneal injection of cadmium 2 mg/kg b.

View Article and Find Full Text PDF

Aldose reductase (AR) is an enzyme implicated in the development of diabetes complications among them diabetic retinopathy. Erythrocyte AR activity was measured in control and diabetic a type-2 diabetic model. We noticed an increase of AR activity in diabetic Meriones by comparison to controls.

View Article and Find Full Text PDF

Background: Rose-scented geranium (Pelargonium graveolens L'Hér.), which is used in traditional Tunisian folk medicine for the treatment of hyperglycaemia, is widely known as one of the medicinal herbs with the highest antioxidant activity. The present paper is conducted to test the hypoglycemic and antioxidative activities of the leaf essential oil of P.

View Article and Find Full Text PDF

The effects of sub-chronic exposure to cadmium (Cd) on the blood glutathione, serum zinc and on the kidney histological organisation in rats as well as the possible protective role of zinc (Zn) are the object of this study. For this purpose, 60 male Wistar rats (8 weeks old) were divided into three groups: the first group was exposed to Cd in the form of CdCl(2), administered in five doses (each of 0.4 mg Cd/kg b.

View Article and Find Full Text PDF

Background: The aim of this work was to investigate the effect of the maturation process of the olive fruit on oil content, phenolic profile and antioxidant activity of four Tunisian cultivars (Zelmati, Chemchali, Chemlali and Chétoui).

Results: The average oil content of the studied varieties ranged between 17.50% and 20.

View Article and Find Full Text PDF

This study was designed to test the antidiabetic and antioxidative activities of olive leaf oleuropein and hydroxytyrosol. Diabetes in Wistar rats was induced by intraperitoneal injections of alloxan. The serum glucose and cholesterol, hepatic glycogen, the thiobarbituric acid-reactive substances (TBARS), and the components of hepatic and serum antioxidant system were examined.

View Article and Find Full Text PDF

Dhokar olive cultivar growing in the south of Tunisia is an unusual olive tree which is characterized by the sweet taste of its fruit. We were particularly interested in the phenolic compounds of this cultivar in comparison to Chemlali cv. During the different maturation stages of olive fruits, the phenolic composition, sugar content, antioxidant activity and enzymatic change were examined.

View Article and Find Full Text PDF

Oleuropein-rich extracts from olive leaves and their enzymatic and acid hydrolysates, respectively rich in oleuropein aglycone and hydroxytyrosol, were prepared under optimal conditions. The antioxidant activities of these extracts were examined by a series of models in vitro. In this study the lipid-lowering and the antioxidative activities of oleuropein, oleuropein aglycone and hydroxytyrosol-rich extracts in rats fed a cholesterol-rich diet were tested.

View Article and Find Full Text PDF

This study was designed to test the lipid-lowering and antioxidative activities of triacetylated hydroxytyrosol compared with its native compound, hydroxytyrosol, purified from olive tree leaves. Wistar rats fed a standard laboratory diet or a cholesterol-rich diet for 16 weeks were used. The serum lipid levels, the thiobarbituric acid-reactive substances (TBARS) level, as an indicator of lipid peroxidation, and the activity of superoxide dismutase (SOD) as well as that of catalase (CAT) were examined.

View Article and Find Full Text PDF

The aim of this study was to assess the effects of subchronic exposure to cadmium (Cd) on the antioxidant defense system of red blood cells (RBCs) and lipid peroxide concentration in the plasma, as well as the possible protective role of zinc (Zn). For this purpose, 60 male Wistar rats (8 weeks old) were divided into three groups: the first group was exposed to Cd in the form of CdCl(2), administered in five doses (each of 0.4mg Cd/kg BW) on days 5, 10, 15, 20 and 25, giving a total dose of 2mg Cd/kg BW, i.

View Article and Find Full Text PDF