Publications by authors named "Hedi Ellefi"
This study aimed to evaluate the antithrombotic, anti-inflammatory and anti-cardiac remodeling properties of eugenol in isoproterenol-induced myocardial infarction in rats. Male Wistar rats were randomly divided into four groups, control, iso [100 mg/kg body weight was injected subcutaneously into rats at an interval of 24 h for 2 days (6th and 7th day) to induce MI] and pretreated animals with clopidogrel (0.2 mg/kg) and eugenol (50 mg/kg) orally for 7 days and intoxicated with isoproterenol (Iso + Clop) and (Iso + EG) groups.
View Article and Find Full Text PDFObjective: Myocardial infarction remains the major cause of global death due to cardiovascular diseases. This study aimed to assess the protective role of oleuropein in attenuating the cardiac remodeling in isoproterenol-induced myocardial infarction in rats.
Methods And Results: Male Wistar rats were randomly divided into four groups, control, isoproterenol (Isop) and pretreated animals with oleuropein at two different doses (20 and 40 mg/kg) orally for 7 days and intoxicated with isoproterenol (Isop+Oleu20) and (Isop+Oleu40) groups.
The present study aimed to investigate the cardioprotective effect of hydroxytyrosol (HT) against isoproterenol-induced myocardial infarction in rats. Male rats were randomly divided into four groups, control, isoproterenol (Isop) and pretreated animals with HT in two different doses (2 and 5 mg/kg) orally for 7 days and intoxicated with isoproterenol (Isop + HT1) and (Isop + HT2) groups. Myocardial infarction in rats was induced subcutaneously by isoproterenol (100 mg/kg, s.
View Article and Find Full Text PDFArticle Synopsis
- - Age significantly affects outcomes for patients with acute coronary syndromes (ACS), particularly those over 65, as ischemic heart disease is a leading cause of death in this age group.
- - The study examined 100 hospitalized patients over 65 with acute myocardial infarction (AMI) and found that the mean age was 77, with most cases being ST-elevation myocardial infarction (STEMI) and a high prevalence of congestive heart failure.
- - Results indicated that invasive treatments, like thrombolytic therapy and primary PCI, improved outcomes both during hospitalization and at one-year follow-up, especially for those over 75 years old.