Writing an effective and succinct cover letter: A practical guide.

Introduction: The cover letter is a critical component of medical journal submissions, often influencing acceptance decisions. However, authors frequently underestimate its importance. This narrative review aimed to provide guidance for authors on writing effective and succinct cover letters.

Prognostic Significance of C-MYC and EGFR Overexpression in Gastrointestinal Stromal Tumors: An Immunohistochemical Study.

Introduction: In addition to mutations in KIT and PDGFRA, many other genetic alterations have been described in gastrointestinal stromal tumors (GISTs), including amplifications of C-MYC and EGFR, which are often associated with increased protein expression. The main of this study was to investigate the prognostic significance of C-MYC and EGFR expression in GISTs using immunohistochemistry (IHC).

Methods: We collected all GIST cases over a 16-year period.

Synchronous occurrence of papillary thyroid carcinoma and solitary fibrous tumor of the thyroid: a case report.

Background: Solitary fibrous tumors (SFT) are ubiquitous mesenchymal neoplasms of intermediate malignant potential. SFTs of the head and neck are rare, representing less than 0.1% of all SFTs.

Relationship Between Cognitive Estimation, Executive Functions, and Theory of Mind in Patients With Prefrontal Cortex Damage.

Objective: Conflicting evidence has arisen from the few studies that have examined the role of the prefrontal cortex and executive control functions in theory of mind (ToM). Moreover, the involvement of other cognitive domains in the ability to infer mental states is still under debate. This study aims to examine, in addition to the potential contribution of executive functions, the role of cognitive estimation in ToM abilities, given that cognitive estimation processes are strongly associated with some aspects of executive control functions.

Impact of Implementing Electronic Nursing Records on Quality and Safety Indicators in Care.

Electronic Health Records (EHR) have been adopted to improve the quality of care. Despite the growing use of health information technology, nursing documentation remains a challenge. In Tunisia, the implementation of the Electronic Medical Record (EMR) system is gaining momentum as part of national initiatives to modernize healthcare.

Teratogenic effect of Misoprostol following failure of elective abortion: A case of femoral agenesis and review of the literature.

Misoprostol, a synthetic analogue of prostaglandin E1, is commonly used in gynecology, particularly in combination with mifepristone for elective abortion. Although its use is widespread, the potential teratogenic effects of misoprostol in cases of failed medical abortion have not been sufficiently explored in the medical literature. Severe congenital malformations, although rare, have been reported, raising concerns about the impact of this drug on fetal development.

Effects of a cardiopulmonary rehabilitation programme on submaximal exercise in Tunisian patients with long-COVID19: A randomized clinical trial.

There is a lack of randomized clinical trials (RCTs) exploring the outcomes of cardiopulmonary rehabilitation programmes (CPRPs) on submaximal aerobic capacity of long COVID-19 patients (LC19Ps). This RCT aimed to evaluate the effect of an ambulatory CPRP on the 6-min walk test (6MWT) data (main outcome: 6-min walk distance (6MWD)) of LC19Ps. Conducted as a single-blinded RCT, the study included Tunisian LC19Ps with persistent dyspnoea (i.

Reasons for consultation in gynecological and obstetrical emergencies among adolescents in Tunisia.

Objectives: The main objective is to study gynecological and obstetrical emergencies among adolescents admitted to the emergency room in our department.

Methods: At the Farhat Hached University Hospital in Sousse's Obstetrics and Gynecology Department, we carried out a retrospective study. Sociodemographic and clinical characteristics of adolescents who consulted over a period of 12 months were described.

Managing scorpion envenomations: A Gabes emergency department case study of 60 patients.

Introduction: Scorpion envenomation constitutes a major public health issue in Tunisia, especially in arid regions such as the Gulf of Gabes. It is necessary to understand the epidemiological and clinical characteristics of this condition and the importance of early management.

Aim: This study aims to assess the epidemiological and clinical profile of patients admitted to the emergency department of Gabes University Hospital for scorpion envenomation, as well as the timing of management and intra-hospital evolution.

A bibliometric analysis of IoT applications in logistics and supply chain management.

The rapid integration of the Internet of Things (IoT) into logistics and supply chain management (SCM) marks a significant transformation towards enhanced efficiencies, security, and sustainability. Through a comprehensive bibliometric analysis of 2680 publications from the Scopus database, this study charts the evolution of IoT within logistics and SCM and reveals a shift from foundational explorations to mature implementations. The research unfolds a complex thematic structure, highlighting the revolutionary impacts of IoT and related technologies such as RFID, the synergy of Industry 4.

Laryngotracheal trauma-induced Macklin effect: A case report.

Laryngotracheal trauma is a relatively rare traumatic injury seen particularly in young male adults. Trauma due to strangulation is one of its most frequent circumstances. However rare, pneumomediastinum is a particular complication of severe blunt neck injuries leading to alveolar ruptures.

Illness perception: A bibliometric study.

Illness perception is a crucial area of study that has seen significant growth and development over the years. This study conducts a comprehensive bibliometric and network analysis of illness perception research, capturing its evolution from 1975 to 2023. Utilizing 1813 publications from the Scopus database, authored by 5428 researchers, we identify key scholars and influential articles in the field.

Predictive Factors for Successful Smoking Cessation in Tunisian Smokers, Sousse-Tunisia: 2015-2020.

Objective: Since 2009, the unit of smoking cessation at Sahloul University Hospital - Tunisia was founded. In this context, the objective of our study was to determine the factors associated with smoking cessation in Tunisian smokers.

Methods: It was a descriptive prospective study over five-years-period 2015-2020.

The role of cognitive estimation in understanding the mental states of others.

Previous studies have emphasized the critical role of the prefrontal cortex in cognitive estimation and theory of mind, however, none of them has questioned the possible role of cognitive estimation processes in understanding the mental states of others. In this study, we compared 30 patients with focal prefrontal cortex damage and 30 control subjects matched by gender, age, and education level on their performances on a cognitive estimation task and two tasks assessing theory of mind: the "Faux-Pas" task and the Reading the Mind in the Eyes task. The results showed that patients were significantly impaired compared with control subjects on both abilities of cognitive estimation and theory of mind.

Harnessing Blockchain to Transform Healthcare Data Management: A Comprehensive Research Agenda.

Properly managing healthcare data is a complex endeavor that must balance the requirements and interests of many stakeholders. In this paper, we present the findings from a panel discussion with healthcare professionals and academics, who elaborate on the current situation in healthcare data management as well as the future role that blockchain could play in this sector. Based on the findings of this panel, we structure the research field of healthcare data management and provide numerous avenues for future research.