Publications by authors named "Heder F G Estrela"
Ethereal Extract of Pepper: Preventing Atherosclerosis and Left Ventricle Remodeling in LDL Receptor Knockout Mice.
Prev Nutr Food Sci
March 2021
Cardiovascular diseases are the leading cause of mortality and morbidity worldwide. In this study we compared the effects of oral treatment with red pepper ethereal extracts or simvastatin on dyslipidemia, left ventricle remodeling, and atherosclerotic lesions of low-density lipoprotein (LDL) receptor knockout mice (LDLr) fed a hyperlipidic diet. Forty 3-month-old male mice were distributed into four groups: control (C; animals fed a standard diet), HL (ani-mals fed a hyperlipidic diet), and HL+P or HL+S (animals fed a hyperlipidic diet plus red pepper ethereal extracts or simvastatin, respectively).
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- The study investigated sympathetic nerve activity in rats with experimental cirrhosis, focusing on renal (rSNA) and splanchnic (sSNA) activities.
- Cirrhotic rats showed increased sSNA but no significant changes in rSNA compared to control rats, along with altered blood pressure and heart rate.
- The findings suggest that baroreceptor impairment affects rSNA and heart rate regulation, indicating early cardiovascular dysfunction linked to liver cirrhosis.
The [Ru(II)(Hedta)NO(+)] complex is a diamagnetic species crystallizing in a distorted octahedral geometry, with the Ru-N(O) length 1.756(4) A and the RuNO angle 172.3(4) degrees .
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