Publications by authors named "Hedan Bai"

Continuous monitoring of biomarkers at locations adjacent to targeted internal organs can provide actionable information about postoperative status beyond conventional diagnostic methods. As an example, changes in pH in the intra-abdominal space after gastric surgeries can serve as direct indicators of potentially life-threatening leakage events, in contrast to symptomatic reactions that may delay treatment. Here, we report a bioresorbable, wireless, passive sensor that addresses this clinical need, designed to locally monitor pH for early detection of gastric leakage.

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Fully implantable wireless systems for the recording and modulation of neural circuits that do not require physical tethers or batteries allow for studies that demand the use of unconstrained and freely behaving animals in isolation or in social groups. Moreover, feedback-control algorithms that can be executed within such devices without the need for remote computing eliminate virtual tethers and any associated latencies. Here we report a wireless and battery-less technology of this type, implanted subdermally along the back of freely moving small animals, for the autonomous recording of electroencephalograms, electromyograms and body temperature, and for closed-loop neuromodulation via optogenetics and pharmacology.

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We introduce damage intelligent soft-bodied systems via a network of self-healing light guides for dynamic sensing (SHeaLDS). Exploiting the intrinsic damage resilience of light propagation in an optical waveguide, in combination with a tough, transparent, and autonomously self-healing polyurethane urea elastomer, SHeaLDS enables damage resilient and intelligent robots by self-healing cuts as well as detecting this damage and controlling the robot's actions accordingly. With optimized material and structural design for hyperelastic deformation of the robot and autonomous self-healing capacity, SHeaLDS provides reliable dynamic sensing at large strains (ε = 140%) with no drift or hysteresis, is resistant to punctures, and self-heals from cuts at room temperature with no external intervention.

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Current spacesuits are cumbersome and metabolically expensive. The use of robotic actuators could improve extravehicular activity performance. We propose a novel method to quantify the benefit of robotic actuators during planetary ambulation.

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Artificial muscles based on stimuli-responsive polymers usually exhibit mechanical compliance, versatility, and high power-to-weight ratio, showing great promise to potentially replace conventional rigid motors for next-generation soft robots, wearable electronics, and biomedical devices. In particular, thermomechanical liquid crystal elastomers (LCEs) constitute artificial muscle-like actuators that can be remotely triggered for large stroke, fast response, and highly repeatable actuations. Here, we introduce a digital light processing (DLP)-based additive manufacturing approach that automatically shear aligns mesogenic oligomers, layer-by-layer, to achieve high orientational order in the photocrosslinked structures; this ordering yields high specific work capacity (63 J kg) and energy density (0.

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Silica-based distributed fiber-optic sensor (DFOS) systems have been a powerful tool for sensing strain, pressure, vibration, acceleration, temperature, and humidity in inextensible structures. DFOS systems, however, are incompatible with the large strains associated with soft robotics and stretchable electronics. We develop a sensor composed of parallel assemblies of elastomeric lightguides that incorporate continuum or discrete chromatic patterns.

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Soft materials possess several distinctive characteristics, such as controllable deformation, infinite degrees of freedom, and self-assembly, which make them promising candidates for building soft machines, robots, and haptic interfaces. In this Review, we give an overview of recent advances in these areas, with an emphasis on two specific topics: bio-inspired design and additive manufacturing. Biology is an abundant source of inspiration for functional materials and systems that mimic the function or mechanism of biological tissues, agents, and behaviors.

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This article introduces a simple two-stage method to synthesize and program a photomechanical elastomer (PME) for light-driven artificial muscle-like actuations in soft robotics. First, photochromic azobenzene molecules are covalently attached to a polyurethane backbone via a two-part step-growth polymerization. Next, mechanical alignment is applied to induce anisotropic deformations in the PME-actuating films.

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