Clinical Implications of High-Sensitivity Troponin Elevation Levels in Non-ST-Segment Elevation Myocardial Infarction Patients: Beyond Diagnostics.

Standard troponin has long been pivotal in diagnosing coronary syndrome, especially Non-ST-Segment Elevation Myocardial Infarction (NSTEMI). The recent introduction of high-sensitivity troponin (hs-cTnI) has elevated it to the gold standard. Yet, its nuanced role in predicting angiographic lesions and clinical outcomes, notably in specific populations like obesity, remains underexplored.

[Prediction of hospital mortality of ST elevation myocardial infarction using TIMI score].

Background: Thrombolysis in myocardial infarction risk score (TIMI-RS) was designed to predict early mortality in patients with a ST elevation acute myocardial infarction (STEAMI).

Aim: To evaluate the predictive capacity for hospital mortality of TIMI-RS.

Material And Methods: Patients with ≤ 12-hour evolution STEAMI were selected from a prospective registry of all patients hospitalized in our coronary unity within January 1988 and December 2005.

[Giant coronary artery fistula: Report of one case].

Coronary artery fistulae are abnormal connections between a coronary artery and any cardiac chamber or other vessels. Most of them have a congenital origin. We report a 60 years old woman referring a history of progressive dyspnea and orthopnea during the last year.

Model-Based Design and Experimental Validation of Control Modules for Neuromodulation Devices.

Goal: The goal of this paper is to propose a model-based control design framework, adapted to the development of control modules for medical devices. A particular example is presented in which instantaneous heart rate is regulated in real-time, by modulating, in an adaptive manner, the current delivered to the vagus nerve by a neuromodulator.

Methods: The proposed framework couples a control module, based on a classical PI controller, a mathematical model of the medical device, and a physiological model representing the cardiovascular responses to vagus nerve stimulation (VNS).

On-off closed-loop control of vagus nerve stimulation for the adaptation of heart rate.

Vagus nerve stimulation (VNS) is a potential therapeutic approach in a number of clinical applications. Although VNS is commonly delivered in an open-loop approach, it is now recognized that closed-loop approaches may be necessary to optimize the therapy and minimize side effects of neuro-stimulation devices. In this paper, we describe a prototype system for real-time control of the instantaneous heart rate, working synchronously with the heart period.

[Features of acute myocardial infarction among aged patients].

Background: Among aged patients, acute myocardial infarction has more complications and there is a tendency to underuse proven treatments.

Aim: To report the features of acute myocardial infarction among aged patients.

Material And Methods: Analysis of a registry of patients with acute myocardial infarction admitted to a coronary unit.

[Primary angioplasty for acute myocardial infarction with an anomalous origin of right coronary artery: report of one case].

Anomalous origin of coronary arteries is a rare anatomical defect and its association with acute myocardial infarction is unusual. We report a 58-year-old male with ST-Segment elevation. Myocardial infarction of the inferior wall caused by a total occlusion on the proximal third of an anomalous right coronary artery, that was effectively treated with primary angioplasty with stent placement.

[Angioplasty compared to thrombolysis as the initial reperfusion therapy in acute myocardial infarction].

Background: Primary angioplasty is superior to intravenous thrombolysis as reperfusion therapy for acute myocardial infarction.

Aim: To compare the results of available reperfusion strategies for initial management of acute myocardial infarction during hospitalization and 5 years follow up.

Patients And Methods: Historical cohort study from a prospective registry of patients admitted with acute myocardial infarction to our center.

[Sub capsular splenic hematoma in a sickle cell trait carrier. Case report].

Drepanocytic anemia is an uncommon hereditary disease in Chile. The heterozygous state of drepanocytic anemia or "sickle trait" has a frequency of 8% among Afro-Americans. A small number of patients carrying hemoglobin S are homozygous, with clinical manifestations of hemolytic anemia and thrombotic disease.

[Coronary artery origin anomalies. Analysis of 10.000 coronary angiographies].

Background: Between 0.3 and 1.3% of coronary arteries, have anomalous origins.

[Clinical features and prognosis of acute myocardial infarction among patients aged 80 years or older].

Background: Subjects older than 80 years have more complicated acute myocardial infarctions and are subjected to less reperfusion procedures.

Aim: To describe the hospital evolution and follow up of patients older than 80 years, suffering an acute myocardial infarction.

Material And Methods: Patients older than 80 years, were selected from a prospective registry of acute myocardial infarction.

[Coronary angiography: indications, results and complications in 5.000 consecutive patients].

Background: There are guidelines about equipment, premises, personnel, indications and complications rates for coronary angiography, that every center performing this procedure should adhere.

Aim: To report the experience with 5.000 coronary angiographies and to assess the compliance of the center with the current guidelines.

[Acute and long-term clinical results of bare metal coronary stenting].

Background: Since the introduction of stents in 1994, improved clinical results have boosted the development of coronary angioplasty in Chile. Drug eluting stents, that have a reduced rate of restenosis, are being increasingly used.

Aim: To assess the acute and long-term results of bare metal stent implantation.